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Biomedical subjects

J F Bach

Publications and source records attributed to J F Bach.

At least 739 records · Page 41Linked to original sources

Appearance of T-cell markers in bone marrow rosette-forming cells after incubation with thymosin, a thymic hormone.

After incubation with thymosin, a thymic hormone, normal bone marrow rosette-forming cells acquire T-cell characteristics, including increased sensitivity to azathioprine, anti-lymphocyte serum, and anti-theta serum. This activity of thymosin provides a new sensitive and reproducible bioassay for thymosin, and is well correlated with an in vivo graft-versus-host assay. In addition, incubation of spleen cells from adult thymectomized mice with thymosin in vitro restores to normal their diminished sensitivity to azathioprine and anti-lymphocte serum.

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