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Biomedical subjects

J Elliot

Publications and source records attributed to J Elliot.

33 records · Page 2Linked to original sources
PubMed1992

The role of descending venography in the management of patients with chronic venous disease of the lower extremity.

The purpose of this paper is to evaluate the efficacy and clinical information obtained from the authors' first 17 consecutive descending venograms. All 17 patients had chronic venous disease refractory to standard conservative and surgical measures. The standard classification of valvular insufficiency was used in evaluating these venograms. There were no deaths, slight morbidity and minimal patient discomfort. In 16 patients meaningful clinical information was derived from the venograms, with 7 patients having deep venous valvular surgery. Descending venography will demonstrate the site of incompetent valves and estimate the degree of reflux. This test is necessary before anticipated reconstruction of deep vein valves.

Chronic Disease↗
PubMed1989

Synthetic parathyroid hormone-like protein-(1-74): biochemical and physiological characterization.

PTH-like protein-(1-74) [PTHLP-(1-74)] was synthesized and purified. On the basis of chromatographic criteria and amino acid composition of the full-length peptide, direct amino acid sequencing of the N-terminus, and amino acid composition and internal sequence of proteolytic fragments of PTHLP-(1-74), the synthetic peptide appears to be of high quality and purity. Physiological comparison of PTHLP-(1-74) to [Tyr36]-PTHLP-(1-36) amide and bovine (b) PTH-(1-34) indicates that all three peptides are of equivalent potency in the fetal rat long bone and rat osteosarcoma 17/2.8 adenylate cyclase assays. However, as in earlier studies with native and N-terminal PTHLPs, PTHLP-(1-74) is considerably less potent (2%) in stimulating the canine renal cortical adenylate cyclase assay than is bPTH-(1-34). Further, PTHLP-(1-74) displayed only 12% of the activity of bPTH-(1-34) in inducing hypercalcemia when infused into rats in vivo. These studies support the possibility that subclasses of PTH receptors or varying PTH- and PTHLP-signalling transduction mechanisms may exist. In addition, they emphasize the need to precisely define the naturally occurring secretory and circulating species of this novel class of peptide hormones.

Adenylyl Cyclases↗
PubMed1987

An inquiry into staffing, organisation and teaching in South African medical schools.

A comparative analysis of student/staff ratios (SSRs) revealed a very marked difference (2:1-5.3:1) between the most and least liberally staffed medical schools in South Africa. A study of workloads determined how the average medical teacher allocates time between teaching, clinical work, research and other activities. How medical teachers teach, their preparation for teaching, factors influencing teaching practices, teaching methods used and their attitudes to the use of educational resources were investigated. Just over 70% of medical teachers are teaching without any formal preparation although opposition to teaching courses appears to be diminishing. That medical education is teacher-orientated is obvious from the fact that resources that transmit information are used more than those that propagate interaction between teacher and student and encourage more complex forms of learning. Only 13% of medical teachers 'often' use educational objectives and the majority (58%) never use them at all. Criterion-referenced evaluation should have a place in medical education, where a core of minimum knowledge is considered essential, but over 80% of medical teachers 'never' use this method in assessing students.

Attitude↗
PubMed1982

A microteaching experiment at MEDUNSA.

Microteaching is a simplified teaching situation enabling novice teachers to practise their teaching skills. At MEDUNSA microteaching was incorporated into an induction course on teaching and learning, and participants were able to practise preparations, design and the presentation of good explanations. The presentations were recorded and played back on videotape. This provided multiple feedback and reinforcement via self-diagnosis and comments from teaching colleagues and a supervisor using questionnaires. The experiment was well received by participants and hopefully generated an interest in improved teaching via the analysis and monitoring of their own teaching performances.

Educational Measurement↗
PubMed1981

Selecting medical students at MEDUNSA. A preliminary report.

Because of the advantages involved, the 1981 intake of M.B. Ch.B I students to MEDUNSA were provisionally selected on the basis of their school record marks and their performance in the Academic Aptitude Test. However, when the latter scores were correlated with the students' matric. results they were found to have poor predictive value as a measure of success in the matriculation examination.

Educational Measurement↗