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Biomedical subjects

J Eldrup

Publications and source records attributed to J Eldrup.

35 records · Page 2Linked to original sources
PubMed1985

Distribution of xenon-133 in mice from the urinary bladder.

The distribution of 133Xe from the bladder was investigated in sliced mice at autoradiography and quantitatively by counting tissue samples from the abdomen and thoracic cavity. Xenon is a highly diffusible inert gas that passes the bladder urothelium. In living mice activity could be seen in the intra-abdominal fat, liver and kidneys; the activity in the kidneys depended on reflux through the ureters. The xenon gas was found in the highest concentration in the lungs where it is expired. The study confirms the assumption that instillation of xenon in the bladder can be used as an indicator for permeability and flow in the wall of the urinary bladder.

Animals↗
PubMed1983

Permeability and ultrastructure of human bladder epithelium.

Leakage of tight junctions as observed with electron microscopy and demonstration of solute transport across bladder epithelium was investigated in 13 patients with different bladder diseases: urinary retention and infection, bladder tumours and interstitial cystitis. The latter group showed consistent leakage of solutes through the urothelium. Electron microscopy revealed leaky tight junctions. This finding might be helpful in establishing the histological criteria and explain the pathogenesis of interstitial cystitis.

Adult↗
PubMed1981

Appendico-vesical fistula and persistent urachus in a patient with hematuria.

A 35-year-old man had been treated with sulfamethizole on 6 occasions because of recurrent urinary tract infections. Furthermore, he had experienced diffuse monosymptomatic hematuria for 15 years. Cystoscopy and biopsy demonstrated irregular intestinal mucosa. Physical examination and intravenous urography were normal. Preoperative diagnosis was urachus-derived adenoma with the possibility of adenocarcinoma. At operation a typical urachus and--surprisingly--an appendico-vesical fistula was found.

Adult↗
PubMed1981

Randomised trial comparing Proximate stapler with conventional skin closure.

The Proximate stapler was compared with usual skin closure in a randomized trial, with 137 patients having elective abdominal and breast surgery. The median duration of skin closure with the Proximate stapler was 80 seconds, which was significantly shorter than the median of 242 seconds with conventional closure. No difference was found with regard to wound infection, but pain was more frequent after stapling.

Clinical Trials as Topic↗
PubMed1980

Influence of orchidopexy for cryptorchidism on subsequent fertility.

The concentration of spermatozoa in ejaculate from testes that had been subjected to orchidopexy during childhood was studied in semen samples taken after unilateral vasectomy of the contralateral normal testis in 4 patients. The counts were extremely low, which suggests that this operation does not improve fertility later in life. Sperm concentration is not influenced by unilateral vasectomy or by inguinal herniotomy during childhood.

Adult↗
PubMed1980

Pancreatic ascites. Intraoperative localization of the pancreatic fistula.

Pancreatic ascites can be diagnosed by demonstration of high amylase concentration in the ascites and ERCP may serve to identify the causal internal fistula. Intraoperatively a precise localization of the ductal leakage is helpful. In two patients we demonstrated the fistulas by stimulation of the pancreatic secretion with secretin.

Adult↗
PubMed1979

High incidence of undetected neoplasia in maldescended testes.

Testicular biopsy specimens from 4 (8%) of 50 men previously treated for maldescended testes had a carcinoma-in-situ pattern. 2 of these men had adjacent invasive carcinoma (seminoma and embryonal carcinoma). The patient with embryonal carcinoma had an enlarged testis but the 3 other patients with neoplasia had no clinical signs or symptoms of malignancy. Routine follow-up including testicular biopsy in young men with maldescended testes is essential because of the increased risk of malignancy and may detect testicular neoplasia at a stage when orchidectomy alone is curative.

Adolescent↗