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Biomedical subjects

J Ehrlich

Publications and source records attributed to J Ehrlich.

At least 37 records · Page 2Linked to original sources

The masticatory pattern as an adjunct for diagnosis and treatment.

The sagitally-viewed masticatory pattern was investigated in 125 dentate patients. In 25 patients, the phenomenon of an incisal guided phase during mastication was observed. Clinical examination of these cases revealed slight to severe incisal attrition or various degrees of flaring. The hypothesis that the incisal guided phase contributes to this phenomenon and should therefore be taken into consideration during treatment is put forward.

Adult↗

Detection of herpes simplex virus in gingival tissue.

The presence of herpes simplex virus (HSV) antigens was shown by immunofluorescence staining in 26 of 66 (39.3%) specimens of clinically healthy gingiva, but only one sample contained infectious virus. HSV DNA sequences were clearly identified in intact gingival cells by dot blot hybridization in one specimen, and a weak pattern in a second one. Both specimens harbored viral antigens. These findings of viral genome and protein expression suggest that the virus is present in the latent form in the gingiva.

Adult↗

Iatrogenic exfoliation of a tooth following abuse of a rubber dam: a case report.

This report presents a case in which tooth exfoliation followed rubber dam abuse. A 40-year-old patient was referred to the prosthodontic clinic with complaints of mobility and discomfort in tooth 44, which had received an amalgam restoration. While this tooth was scaled, a piece of rubber dam appeared in the buccal sulcus. Removal of the rubber piece was followed by thorough scaling and tooth splinting. Tooth deterioration continued, and concern for the adjacent teeth necessitated extraction of tooth 44. To avoid such undesirable consequences, the integrity of the dam should be verified on its removal.

Adult↗

Effect of occlusal bite-raising splint on electromyogram, motor unit histochemistry and myoneuronal dimensions in rats.

Composite resin bite-raising splints were fabricated on both sides of the upper jaw in rats. EMG activity of the deep masseter muscle was monitored continuously for 24 h before and up to 4 weeks after treatment. Together with the EMG activity, measurements of the neuromuscular junction area and muscle fibre histochemistry were made. EMG activity showed great variability immediately after splint fabrication. Some of the animals showed increased EMG activity, while others exhibited less activity 48 h after splint application. Overall, the fluctuation lasted for about 4 days, and after approximately 7 days all the animals exhibited decreased EMG activity, followed by a gradual increase in activity towards baseline levels. The neuromuscular junction territory increased significantly 5-10 days after splint application. Histochemical characterization of the deep masseter muscle revealed that it contained the three main types of muscle fibre: slow oxidative (SO), fast-oxidative-glycolytic (FOG) and fast glycolytic (FG). The frequency distribution of fibre types did not change after bite-raising splint treatment. These findings indicated that splint treatment in rats is effective in reducing EMG activity, while the muscle type characteristics remain stable. The effect of lower activity on the motor end-plates suggested that the neuromuscular junctions are quite sensitive to functional changes.

Adenosine Triphosphatases↗

Functional and esthetic rehabilitation of an adolescent cleft lip and palate patient.

Many patients with clefts that also affect the alveolar ridge present with congenital absence of the permanent maxillary lateral incisors. This paper describes the treatment of an adolescent cleft lip and palate patient whose missing and unesthetic maxillary incisors were replaced by a combination of fixed and removable partial dentures.

Adolescent↗

Various methods in achieving anterior guidance.

The anterior teeth are essential for esthetics, phoentics, and mastication and are equally involved in protecting posterior teeth. A 10-year longitudinal study of treatment modalities was conducted for overbite-overjet occlusal relationships. Comprehensive treatment combining orthodontics, occlusal adjustment, and selective restorations minimized the need for extensive restorative dentistry. The treatment of selected patients with a 10-year postoperative evaluation was discussed.

Adolescent↗

Severe vertical overlap: a modified method of treatment.

Severe vertical overlap may predispose the patient to abnormal function, improper mastication, excessive stress, and functional problems such as bruxing, clenching, and craniomandibular disorders. This report describes the establishment of a new occlusal relationship by using the potential of posterior tooth eruption with the Hawley bite plane or the canine platform method. It was used in patients with a full complement of teeth or with some missing teeth. Patients treated by either the Hawley bite plane or the canine platform demonstrate a stable and long-lasting new occlusal relationship. The method described is efficient, inexpensive, and convenient to the patient.

Bicuspid↗

Oral cavity herpes simplex virus--a risk factor to dental personnel and patients. An overview.

Herpes virus antigens were found in the sulcular epithelium of approximately 60% of patients with clinically healthy gingiva. In addition, specific antigens for herpes simplex virus (HSV) were found in the sulcular epithelial cells of patients undergoing periodontal treatment. Specific antibodies were also detected in 70-80% of the gingival fluids collected. On the basis of these data we hypothesized that the oral cavity may act as a preferential site for latent HSV. Thus, stressful events such as traumatic dental treatment and tissue damage may elicit herpetic episodes, risking dental personnel. Measures of precaution are indicated for routine dental treatment.

Antigens, Viral↗

The functional range of tooth contact in lateral gliding movements.

The dynamic contact pattern of teeth in lateral glide movement was recorded in 72 individuals, 19 to 35 years of age, with normal tooth alignment and Angle class I molar and canine relationship. The lateral glide movement was divided into three stages to simulate the total range of events in lateral glide movement naturally demonstrated by the patient. This study has shown that lateral glide movement is a complex movement in which the nature of tooth contact is altering in location, direction, and number of teeth participating. Consequently the restoration of an occlusion in accordance with a given concept does not always apply to all patients.

Adult↗

The cantilever fixed partial denture: a 10-year follow-up.

A 10-year study of patients with cantilever fixed partial dentures suggests that these prostheses can be used for both anterior and posterior replacements. Guidelines for cantilever prostheses are described. Fixed cantilever prostheses are favorable alternatives to certain types of unilateral removable partial dentures. Proper oral hygiene is essential.

Adult↗

Effect of occlusal (mechanical) stimulus on bone remodelling in rat mandibular condyle.

Mechanical load influences the remodelling of skeletal tissues. In the mandibular condyle, occlusal alterations and the consequent mechanical stimulus induce changes in chondrocytes and cartilage mineralization. In the present study we quantified in the mandibular condyle the effect of occlusal interference on remodelling of the subchondral bone. Computerized histomorphometry after 5-21-day exposure to the influence of a unilateral occlusal splint revealed an increased rate of trabecular remodelling, consisting of enhancement in osteoblast and osteoclast numbers and activities. The bone formation parameters reached their high values on Days 5 or 9 and remained stable thereafter. Bone resorption showed a gradual increase throughout the experimental period. These results further characterize the temporomandibular joint reaction to occlusal alterations. It is suggested that the present increase in bone turnover together with the known enhancement in chondrogenesis are part of a process of functional adaptation in response to mechanical stimulus.

Animals↗

Hypothesis: the gingival tissue as a reservoir for herpes simplex virus.

The reservoir site of Herpes simplex virus (HSV), from the primary infection until reactivation and in between recurrences was found to be in the dorsal roots of the trigeminal ganglion or in the sensory root ganglion. However, the triggering of viral genome in the ganglion does not exclusively explain the recurrences and appearance of skin lesions. Other sites cannot, therefore, be excluded, and virus may well be occult also in extraneural tissues. Herpes virus antigens were found by us in the sulcular epithelium of approximately 60% of patients with clinically healthy gingivae; we therefore hypothesised that the epithelial cells might act as the preferential site for latent HSV. In order to prove this assumption, viral genome should be traced in cells of oral tissues, and efforts should be made to rescue virus.

Antibodies, Viral↗