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Biomedical subjects

J Eckert

Publications and source records attributed to J Eckert.

At least 199 records · Page 11Linked to original sources
PubMed1979

[Chemotherapy of human echinococcosis with mebendazole (Vermox): preliminary clinical results].

Two patients with inoperable multiple Echinococcus granulosus infections involving the lungs and the liver (one patient) were treated with the following daily doses of mebendazole (Vermox): 3 days 1000 mg, 3 days 1500 mg, the following 3 months 30-40 mg/kg body weight. One of the patients had been treated before with mebendazole in similar doses for 3 periods of 5-6 weeks each. The patients received the drug as 500 mg tablets divided into 3 daily doses after meals. After termination of treatment a distinct regression of lung cysts was demonstrable in both patients, with the exception of one cyst. The liver cyst in one of the patients had also decreased in size. About 8 months after therapy signs of reactivation of lung cysts were observed in one patient, and a new course of mebendazole treatment was therefore started.

Adult↗
PubMed1979

[Prediction of the effects of client-centered psychotherapy on the basis of an indications interview].

Several effects of client-centered therapy were predicted on the basis of a short intake-interview divided into two parts: an exploration-phase and a quasi-therapy-phase. Elements of the international behavior and elements of the intrapersonal exploration of the client were rated by neutral observers and served as predictor variables as well as ratings of the experiences in the two interview situations by the client himself. Our population were 29 out-patients of a psychiatric clinic. We could demonstrate, that on the basis of an 45-minutes intake-interview it is possible to make a rather good prediction of the therapy outcome -- measured by several clinically relevant personality scales -- though therapists and interviewer were not identical and though there was a waiting period of several weeks between the interview and the start of therapy and though the therapists were rather unexperienced.

Communication↗
PubMed1978

[Strongyloidiasis following kidney transplantation].

A 50-year-old Swiss male died from strongyloidiasis 8 weeks after renal allotransplantation. Past history revealed malaria at age 20 years, when the patient had stayed in tropical and subtropical areas, as well as pulmonary tuberculosis. Hypertension, erythrocyturia, proteinuria and unexplained episodes of blood eosinophilia were first noticed age 45, and 4 years later dialysis was started. A mild acute rejection crisis was successfully treated 4 weeks after transplantation. 2 weeks later, however, bilateral pneumonia developed. Despite vigorous antibiotic and tuberculostatic therapy the patient died in septic shock. Autopsy revealed strongyloidiasis with adult females, eggs and rhabditiform larvae of Strongloides stercoralis in the small intestine. Numerous filariform larvae were detected in the lungs, in the walls of bronchi and trachea, in the brain, in the walls of arteries, and in lymphnodes. Massive granulomatous inflammatory reaction and extensive pulmonary hemorrhage were the main pathological findings.

Chronic Disease↗
PubMed1977

Detection of the Echinococcus granulosus diagnostic arc 5 in sera from patients with surgically-confirmed E. multilocularis infection.

The Echinococcus granulosus diagnostic arc 5 was revealed by sera from an Alaskan and a Swiss patient with surgically confirmed E. multilocularis infections. The possibility of each patient harboring a concurrent infection with both parasites may be disregarded on the basis of radiologic, scintillographic and surgical data. This conclusion is compatible with ecologic and epidemiologic considerations. These observations suggest that the immunoelectrophoresis test based on arc 5 positivity is not E. granulosus-specific as originally described.

Adult↗
PubMed1977

[Ideas on the part of patients and doctors regarding the adequacy of psychiatric inpatient and outpatient treatment (author's transl)].

One fixed day the doctors of a Psychiatric University Clinic were asked what form of therapy would be best for each of their inpatients (n = 164), and whether these patients could leave the inpatient treatment in case the desired ambulant therapy institutions existed. Half a year after this inquiry questionnaires were sent to the patients, and 104 replies were received. The opinions of the patients which treatment would have bee best for them were compared the doctors' judgements. Both, doctors and patients wanted more ambulant therapy opportunities than existed. There was little unity between doctors and patients about the question with patient would profit from what sort of therapy. We assume that a deciding factor in this disagreement between doctors and patients is the doctor-patient-relationship.

Adult↗
PubMed1976

The cheating and intention of a partner as determinants of evaluative decisions among juvenile offenders.

Male juvenile offenders were asked to evaluate the work of an experimental partner (confederate) who completed a work task four times. The work partner cheated on two trials and did not cheat on two trials while working for a charity (one cheat and one noncheat trial) or for selfish gain (one cheat and one noncheat trial). It was found that subjects rated the work done on cheating trials lower than work done on noncheating trials. In addition, subjects shared less reward money on cheating trials relative to noncheating trials. However, the intentions of the conferate, defined as the reward recipient, failed to affect subjects' judgments. These results were described as supporting previous studies which have indicated that delinquent fail to account of others' intentions when making moral judgments.

Adolescent↗
PubMed1976

Diffuse hair loss in women: the psychopathology of those who complain.

Thirty-two women complaining of diffuse alopecia were examined by a psychiatrist. Seven of them were found to have severe, usually long-standing marital and sexual problems and two of them were overtly depressed. In a previous investigation the results of tests to assess the degree of hair loss of these seven women showed no significant difference from the values obtained in a control series of women. The psychopathology underlying this complaint is discussed and it is suggested that those women whose anxiety seems disproportionate to their degree of hair loss should be carefully questioned regarding depression and marital difficulties as these may cause them to be unusually sensitive to a hair loss which normally might not worry them sufficiently to seek further advice. They may then use their hair in a symbolic way to obtain help with their underlying problems.

Adult↗
PubMed1976

[On the effect of mebendazole on metacestodes of Mesocestoides corti and Echinococcus multilocularis (author's transl)].

Mebendazole (5-benzoyl-2-methoxycarbonylaminobenzimidazole) was highly effective against tetrathydridia of Mesocestoides corti in the peritoneal cavity, liver and in the subcutis of mice when administered orally in the food (450 or 465 ppm) from days 7 or 40/50 post infectionem (p.i.) for 10 or 20 days in total doses of approximately 660-1660 mg/kg body weight (b.w.). All tetrathyridia were killed when treatment began at day 7 p.i., and only some survived when medication was started on days 40/50 p.i. A treatment of 5 days was only partially effective. In experiments with Echinococcus multilocularis laboratory animals were intraperitoneally infected with metacestode tissue transplants. Beginning on days 4-7 p.i. or on day 40 p.i. the animals were treated for 5, 10 or 20/21 days with mebendazole medicated food. In mice a treatment for 10 or 20/21 days with total mebendazole doses of approximately 660-2180 mg/kg b.w. caused an average reduction on metacestode weight of 61-89%. An average reduction between 58 and 84% was achieved in Meriones after a treatment for 20/21 days with total doses of approximately 650/530 mg/kg b.w. However, histological examinations and transplantation experiments revealed that in most of the treated animals metacestode tissue survived and retained its capability for budding. On the other hand, indications for a partial destruction of the parasite tissue were found in some of the treated animals. The oral mebendazole treatment was well tolerated. After intraperitoneal injection of 3 X 150 mg/kg b.w. mebendazole - as applied by Campbell et al. (1975) - all of 36 mice or Meriones died.

Animals↗