Effects of supplemental selenium on swine. I. Gestation and lactation.
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Biomedical subjects
Publications and source records attributed to J E Wilkinson.
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The investigation was carried out to design and test more purposeful and structured methods of promoting intellectual growth in culturally deprived preschool children. The relative merits of providing specific cognitive training both in a nursery setting and in the home through the influence of the mother were assessed. Four groups each of 15 children were involved in the experiment, which extended over a period of four months. Gains were confirmed for both general intelligence and linguistic competence. Both the two nursery groups and the experimental "home" group all showed considerable improvement, the latter being comparable to the nursery control group.
Using a test-observe-test design with a sample of 29 4-year-old children, this exploratory study investigated associations between activity choices in a typical progressive nursery school and IQ, socio-economic status (SES) and sex. Over the 4-month period of the study the group as a whole displayed enhanced intellectual capacity through several children failed to show improvement. These losers spent more time on physical and non-play activity and more time unoccupied. The low SES group spent more time alone, more time on social-personal activity, more passive time with adults and more time on solitary play. Clear sex differences in activity choice were found.
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Plasma cell myelomas in horses have been reported infrequently. Data from 10 cases, 9 from the literature and 1 new case, are used to characterize the disease in the horse. Hot-blooded horses (7/10), specifically Quarter Horses (4/10), were most often affected. Median age at diagnosis was 11 years (range, 3 mo-22 yr) and both male (5) and female horses (5) were represented equally. Clinical findings included weight loss (6/8), anorexia (4/8), fever (4/8), limb edema (4/8), pneumonia (3/8), rear leg paresis/ataxia (3/8), epistaxis (3/8), palpable lymphadenopathy (2/8), and bone pain (2/8). Anemia (8/8) was present routinely, and in three horses, RBCs were macrocytic. Leukopenia (2/8), thrombocytopenia (2/8), and circulating plasma cells (3/8) were variable findings. Except for abnormal protein concentrations and hyponatremia (3), abnormal results from serum biochemical analysis including hypocholesterolemia (1), hypercalcemia (1), and azotemia (1) were reported infrequently. Hyperproteinemia (8/9), hypoalbuminemia (7/9), and hyperglobulinemia (8/9) were characteristic but not invariable findings. Monoclonal proteins (7/7) were detected in the alpha 2, beta, or gamma region by serum electrophoresis. The paraprotein's heavy chain, determined in four horses, was a subclass of IgG. Three horses had decreased concentrations of normal immunoglobulins. Variable proteinuria (trace to 4+) was detected by routine urinalysis in four of six horses. Bence Jones proteinuria was detected in one of five horses (heat precipitation) and monoclonal proteins were detected in two of three electrophoresed urine samples. Three of the horses had lytic bone lesions detected radiographically. Bone marrow aspirates were diagnostic in two of five horses.(ABSTRACT TRUNCATED AT 250 WORDS)