Case report of achondroplasia.
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Biomedical subjects
Publications and source records attributed to J E Riley.
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Nurses need to be actively involved in current research on TENS therapy. A thorough in-service training program for all nurses involved in the TENS program must be developed in order for nurses to knowledgeably assist their patients in maximal adaptation to TENS therapy. Transcutaneous electrical nerve stimulation therapy is not a panacea in postpartal pain management. It can be argued that TENS is another extension of technology interfering with the original natural simplicity of the birthing process; however, further research in the technique needs to be conducted before TENS can be rejected as such. Ultimately, the goal of postpartal care for the cesarean-birth family is to allow the parents to enjoy the birth experience without the dangers of the past and the, at times, unnecessary interference of the present. TENS therapy may be a means toward that end.
Diversion of portal blood in congenital portosystemic shunts (CPSS) results in liver atrophy and passage of toxins into the systemic circulation causing hepatic encephalopathy. In some dogs, there is indirect evidence for hepatic insufficiency, but histologic findings are equivocal. This study determined whether hepatocyte integrity in PSS is comprised at a subcellular level using analytical subcellular fractionation of liver biopsies. Six dogs with CPSS had hypoproteinemia (6/6), increased serum alkaline phosphatase (6/6) and alanine aminotransferase (4/6) activity, hypocholesterolemia (6/6), and decreased blood urea (2/6). Liver biopsy specimens had increased activities (mU/mg protein) of alkaline phosphatase (17.9 +/- 10.1; controls 5.1 +/- 5.3: P less than 0.01), but not of other plasma membrane enzymes. There were increased activities of endoplasmic reticular (neutral alpha-glucosidase: 1.67 +/- 0.7; controls 0.86 +/- 0.2: P less than 0.01) and lysosomal enzymes (N-acetyl-beta-glucosaminidase: 12.6 +/- 2.3; controls 6.24 +/- 2.7: P less than 0.01; alpha-mannosidase: 0.85 +/- 0.5; controls 0.39 +/- 0.3: P less than 0.05). Subcellular fractionation on reorientating sucrose density gradients showed a high-density peak of alkaline phosphatase suggestive of a specific increase in the biliary canalicular component of enzyme activity. Neutral alpha-glucosidase was shifted to denser fractions, indicative of an increase in the proportion of rough-to-smooth endoplasmic reticulum and consistent with enhanced synthesis of membranous enzymes. There was also evidence for increased fragility of intracellular organelles, particularly lysosomes. In contrast, histology showed either no abnormalities or minor degenerative changes compatible with hepatic underperfusion.(ABSTRACT TRUNCATED AT 250 WORDS)
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This study was designed to identify the determinants of postoperative work status among 47 heart transplantation patients at the University of Arizona Medical Center and to focus attention on those actions or policies that increase the probability that a patient will return to work within 6 months after transplantation. Issues regarding work status, disability, and early retirement have become increasingly salient. Case study methods were employed to assign each of the patients to one of four categories, which together form a typology of postoperative work status. Analysis of the patients identified four major variables of work status: age, length of disability before transplantation, control over working conditions including job redefinition/discrimination, and type of health insurance including cost of medication. Although these variables are interdependent, each also has an independent effect on postoperative outcome. The study concludes that although age and length of disability before transplantation cannot be directly affected, both control over working conditions and types of insurance are amenable to intervention.
The following is a case report of an unusual complication after heart transplantation. The patient was a 37-year-old man who underwent heart transplantation because of idiopathic cardiomyopathy. His postoperative course was complicated by cardiac tamponade, coagulopathy, and chronic constrictive pericarditis. After transplantation, he underwent three subsequent open-chest procedures: the first for tamponade, the second for Serratia mediastinitis, and the third for a pericardiectomy for constrictive pericarditis. Although constrictive pericarditis and pericardiectomy have been described following coronary bypass surgery and valve replacement, they have not yet been reported in a heart transplant recipient.
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Dental Medicaid, an essential health adjunct for many indigent people, is seen from the standpoint of a New York State dentist auditor. A few professionals may be abusing the system to the detriment of the majority. How to follow the rules and avoid costly audits.