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Biomedical subjects

J E Paillas

Publications and source records attributed to J E Paillas.

At least 19 recordsLinked to original sources

A review of 2,413 tumours operated over a 30-year period.

Studying 2,413 cases of supratentorial brain tumors operated on a 30 years period, the author emphasizes appealing signs, pitfalls, and tumoral relapses. Epilepsy is the most frequent initial sign preceding headache and focal signs. We discuss the frequency of the epilepsy, the age of the first seizure, the location and the histological nature of the epiletogenic tumor, and the type of the seizures. In the end, we study diagnosis pitfalls such as long-standing epilepsy, ictal presentation, pitfalls due to metastases and the difficult problem of tumoral relapses.

Adolescent↗

Haemangioblastoma of the brain. Computed tomography and angiographic studies in 17 patients.

Between 1975 and 1983, 17 patients who underwent surgery for haemangioblastomas of the brain (16 lesions occurring in the posterior fossa) were studied with CT scans (17 cases) and vertebral angiograms (15 cases). The CT scans were superior for demonstrating a cystic tumour, its topography in the posterior fossa, its relationship to the fourth ventricle, and the presence and degree of an obstructive hydrocephalus. The vertebral angiographies were more sensitive and specific than CT for revealing the vascular nature, and were imperative in order to establish the supply and drainage of the tumours. It is clear that CT and angiography each make an important contribution toward defining these tumours. Their association is necessary.

Adolescent↗

Long-term results of conventional surgical treatment for epilepsy. Delayed recurrence after a period of 10 years.

The results of the surgical treatment of epilepsy were studied in 44 patients 10 or more years after operation. Thirty-seven patients underwent operation only once; these patients were observed 11-26 years postoperatively. Seven patients had a recurrence within 5 years after operation and required a second operation; these patients were observed 11-17 years after the second operation. Recovery persisted for 15-27 years in 32 patients. There was a recurrence in 12 cases 11-19 years after operation. With one exception, these recurrences were satisfactorily treated medically.

Adolescent↗

[Advances in diagnosis and treatment of oligodendrogliomas of the brain. Eighty-four surgical patients (author's transl)].

The authors report their experience of 84 patients with oligodendroglioma seen over a 34 year period. The low incidence of these brain tumors is underlined. Oligodendroglioma is the most epileptogenic of brain tumors. The clinical picture may resemble "essential" epilepsy. Normal EEG should be considered suspect in confirmed epileptic children and adolescents since oligodendroglioma is the most common of all tumors which induce long-standing epilepsy. Emphasis is put on the importance of computerized tomography and radionuclide scanning for early detection of these tumors. Both procedures are very helpful for deciding on the best operative approach and for determining whether the lesion is malignant or not. The authors advise tumorectomy, which should be as complete as possible, followed by systematic radiotherapy, even if histopathological criteria indicate a benign tumor. With this therapeutic regimen mean survival rates are significantly higher than those published previously.

Adolescent↗