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Biomedical subjects

J E Christ

Publications and source records attributed to J E Christ.

27 records · Page 2Linked to original sources
PubMed1979

An analysis of circadian rhythmicity of heart rate in tetraplegic human subjects.

Eight tetraplegic human volunteer subjects from the Veterans Administration Hospital in Houston, Texas, had their heart rates monitored at half-hour intervals for 24 hours. Autocovariance analysis demonstrated circadian rhythms of heart rate in four chronic tetraplegic subjects and one acute tetraplegic subject. The remaining three subacute tetraplegic subjects demonstrated no circadian rhythmicity of heart rate. It is postulated that central denervation of the heart from the sympathetic division of the autonomic nervous system in cervical cord injury results in loss of circadian rhythmicity in heart rate until the vagus of the parasympathetic division obtains control, sympathetic spinal cord centres re-establish control, or an orderly interaction of both occurs. Further study appears indicated.

Adult↗
PubMed1975

An analysis of the circadian rhythmicity of atrial and ventricular rates in complete heart block.

A 19 year old female human subject with complete heart block was put at complete bed rest for 63 hours during which a Lead II EKG was monitored at half hour intervals. Atrial and ventricular rates demonstrated cyclic activity with peaks during the day and troughs during the night. A correlation coefficient of plus 0.85 and a slope of plus 1.0 from a linear regression between atrial and ventricular rates demonstrated a close parallel. Calculation of the crosscovariances confirmed the observed cyclic activity with a period of 24 hours and phase angle of zero degrees between the two chambers. The data may be explained by one or all of the following mechanisms: (1) both chambers are subject to the same internal milieu, (2) autonomic nervous system discharge and associated reflexes may integrate relative changes in rate, (3) direct mechanical or electrotonic forces may result in alteration of rates in direct proportion to the magnitude of the dominant chamber, (4) program which operates independent of external factors. The question remains for direct experimental data to demonstrate whether the observed phenomenon is an intrinsic biologic rhythm within the heart or in its control system.

Adult↗
PubMed1975

The residual ovary syndrome.

Previous reports have demonstrated a significant incidence of pelvic symptomatology involving ovaries preserved following hysterectomy, to be called "the residual ovary syndrome." This report, in an 11-year retrospective analysis of all oophorectomies at The Methodist Hospital in Houston, Texas, identified 202 cases in which a previous hysterectomy had been performed. The majority of these patients presented with varying degrees of chronic pelvic pain (77.2%), asymptomatic pelvic mass (14.4%), and dyspareunia (67.0%). The incidence of malignant neoplastic change in these patients was 3.0%, related to whether hysterectomy was performed before or after the age of 40. In view of the incidence of the residual ovary syndrome and the risk of malignant neoplastic change when hysterectomy is performed after the age of 40, serious consideration of total ovarian ablation at the time of hysterectomy should be weighed against any temporary physiologic and/or psychologic benefits to be gained from conservation.

Adult↗
PubMedDate not supplied

Rapidly evolving non-parasitic hepatic cyst.

A case of solitary non-parasitic hepatic cyst is presented; its evolution appears to have occurred rapidly (10 months). This and all previously reported cysts are unassociated with any clearly diagnostic signs, symptoms, laboratory or x-ray findings. The treatment of choice is total surgical extirpation since the incidence of recurrence of the cyst is appreciably high with subtotal excision, drainage, and marsupialization. This disease has been reported to carry a mortality of 5.1% to 6.6%.

Acute Disease↗