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Biomedical subjects

J Dziezyc

Publications and source records attributed to J Dziezyc.

23 records · Page 2Linked to original sources
PubMed1989

Effects of lipoxygenase inhibitors in a model of lens-induced uveitis in dogs.

Uveitis was induced in dogs by intracameral injection of canine lens protein. The lipoxygenase inhibitors phenidone and norhydroguaiaretic acid, and dimethyl sulfoxide decreased fibrin production at 0.5 and 1 hour after induction of uveitis. Phenidone and norhydroguaiaretic acid also inhibited the initial increase in intraocular pressure early in the course of inflammation. Leukotriene B4 in the aqueous was measured by use of radioimmunoassay at 1 hour after inflammation. In control dogs, 230 to 1,700 pg of leukotriene B4/ml was measured; in dogs treated with phenidone, leukotriene B4 was not measured.

Animals↗
PubMed1986

Surgical repair of rhegmatogenous retinal detachments in dogs.

One to five weeks after cataract removal, retinal detachments due to retinal breaks (rhegmatogenous detachments) were detected in 4 dogs. Surgical repair of the detachments, using a scleral buckling procedure, was successful in 3 of the 4 dogs.

Animals↗
PubMed1985

Uveitis associated with poliosis and vitiligo in six dogs.

Idiopathic panuveitis with retinal detachment was associated with facial poliosis, vitiligo, and alopecia in 6 dogs; 4 were adult males. Dermatohistologic examination of affected facial sites from all dogs revealed a lichenoid dermatitis and unusual histiocytic cells. Intensive topical and systemic corticosteroid and topical mydriatic/cycloplegic therapy was successful in controlling uveitis in all dogs for variable periods. Three dogs, monitored for 12, 30, and 46 months, retained useful vision despite infrequent recurrence of uveitis. One dog was lost for subsequent examination. Two dogs were euthanatized and necropsied. Ocular histologic examination of these dogs revealed extensive granulomatous iridocyclitis and choroiditis, with retinal detachment and lenticular degeneration.

Adrenal Cortex Hormones↗