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Biomedical subjects

J Due

Publications and source records attributed to J Due.

At least 37 records · Page 2Linked to original sources

Bone scintigraphy, radiographic survey and prostatic acid phosphatase in patients with prostatic carcinoma. A comparison of sensitivity.

In 62 patients with histologically confirmed carcinoma of the prostate bone scintigraphy, radiographic survey and serum prostatic acid phosphatase determinations were carried out to evaluate the progression of the disease and to compare the relative sensitivity of the diagnostic tools. Thirty-five patients had scintigraphic evidence of skeletal metastases, whereas abnormal X-ray survey and elevated prostatic acid phosphatase levels were found in only 4 and 19 patients, respectively, all of whom had positive scintigraphic findings. Radiographic evidence of metastases was not found in any of the patients with normal scintigraphy, while elevated prostatic acid phosphatase was found in two patients. It is concluded that bone scintigraphy is far more sensitive than either radiographic survey or determination of prostatic acid phosphatases in the diagnosis of skeletal involvement in prostatic carcinoma, and should be the method of choice for this purpose.

Acid Phosphatase↗

[Vasectomy].

Explore the source record for details and available documents.

Adult↗

[Contrast medium reaction to iohexol (Omnipaque) with monocyte activation demonstrated in vivo].

A contrast reaction to the intravenous injection of the non-ionic contrast medium iohexol (Omnipaque) is reported. The symptoms developed several hours after the injection and at first were not recognised as being due to the contrast. The reaction could be reproduced under controlled conditions and was associated with a significant rise in thromboplastin synthesis in circulating monocytes, a sign of marked cellular activation.

Adult↗

A simple technique for subcutaneous fasciotomy.

A special instrument was devised for semiblind fasciotomy in the treatment of chronic anterior compartment syndrome of the leg. The instrument has been used to treat 133 legs, with satisfactory results.

Anterior Compartment Syndrome↗

Blood coagulation in patients with benign and malignant tumours before and after surgery. Special reference to thromboplastin generation in monocytes.

In this study we have looked for differences in coagulation parameters before and after surgical removal of benign or malignant tumours. A striking increase in thromboplastin activity of the blood monocytes was seen 1 d after surgery. This paralleled a fall in factor VII activity. At the same time, the sensitivity of the blood monocytes to stimulation by endotoxin increased significantly. We propose from this study that monocyte thromboplastin may be a postoperative thrombogenic factor. Increased levels of factor VIII and fibrinogen 2-3 d postoperatively were found, probably caused by inflammation reactions induced by the surgery. No difference in coagulation parameters could be demonstrated between patients with benign, noninvasive lesions and patients with invasive, carcinomatous lesions.

Blood Coagulation↗

Congenital lumbar "pseudohernia".

At the age of 11 mo, a boy, born by breech presentation, was seen with signs suggesting a congenital lumbar hernia. Signs of already healing epiphysiolysis humeri and costal fractures suggested a traumatic origin of the hernia due to neuropraxia of the intercostal nerves. Full recovery ensued without active treatment.

Hernia, Ventral↗