[Thyroid function after treatment of cancer of the upper respiratory and digestive tract].
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Biomedical subjects
Publications and source records attributed to J Dubin.
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Five further cases of subglottic stenosis after intubation are reported. Lesions were due to chondrolysis of the cricoid cartilage: associating an Evans type anterior laryngotracheoplasty (the principle of which is recalled) with the posterior cricoid incision of the Rethi-Aboulker type produced a marked improvement in the results of posterior laryngoplasty performed alone.
Laryngeal diastema or laryngeal or posterior laryngotracheal cleft is a rare congenital malformation producing an aerodigestive communication of abnormal location which leads to severe or even fatal respiratory and infective complications. Findings in 16 cases are presented and the characteristics and particular problems of treatment of this malformation discussed. Diagnosis is presently based on results of microlaryngoscopic examination. Details are given of therapy of the commonest forms of the affection (cricoidal and upper cricotracheal), operations being performed in 9 such cases, and the place and course of forms limited to the interarytenoidal space discussed. Frequency and effect on prognosis of associated malformation are outlined. Considerable improvement has been obtained in the postoperative prognosis of cricoidal (I) and upper cricotracheal (II) forms during the last few years, and these forms must now be considered as curable.
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Radiopathological examinations were conducted on a frozen laryngeal specimen to determine its characteristics as seen on the CT scan image. Results of CT scan imaging of 37 patients with laryngeal cancer were then compared with results of clinicopathological examination in 20 cases (after fixation and decalcification, the 20 samples were sectioned in axial planes reproducing those of the CT scan as for as possible). The results of computed tomography are conclusive for investigation of tumoral extension to the hyothyo-epiglottic space, and may lead to modification of therapy; they are of marked value for assessment of tumoral extension to the laryngeal cartilages, with the reservation that ossification of these cartilages must be taken into account. Furthermore, they enable assessment of subglottal extension when the respiratory state of the patient or the size of tumor makes it impossible to perform direct laryngoscopy.
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Cold abscesses in the cervical region, without associated general and functional signs, may be tuberculous lymph nodes or infected foci due to atypical mycobacteria. In the former, long-term antibiotic therapy, possibly followed by surgery conducted under conditions applicable to curettage for these lesions, is formally indicated. Treatment is of only moderate value in the second case, and spontaneous healing without other than esthetic sequelae usually occurs. These two lesions are quite different, therefore, but this was not recognized, and confusion still exists in many cases, for two reasons. Firstly, acid-alcohol-resistant bacilli are found in the pus in both cases, and a distinction cannot be made between them without culture. Secondly, pathological examination of specimens removed demonstrates identical appearances. The only way to distinguish between the two lesions, and to avoid excessively long or aggressive treatment, is by means of bacterial culture.
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Rupture of a carotid artery in an infected or irradiated environment is a tragic event that frequently causes immediate death. Plain ligature, when possible, for these patients in a state of shock, leads to cerebral ischemia in 65% of cases. This can be prevented, if one operates soon enough by an extra-anatomic by-pass, avoiding the infected or irradiated area, between the subclavian artery and the homolateral carotid artery. (Study of 2 cases). Such a procedure could be used preventively when the risk for the carotid is highest (particularly septic surgery followed by irradiation).
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The tube-bougie methode suggested by the authors ten years ago for dilatation of oesophageal stenosis is based upon the fact that the instrument dilates only in the oesophagus itself and that it consists, on the one hand at the level of the stomach and secondly at the level of the nose and pharynx of a tube a small calibre which makes it possible to leave the dilating instrument in place for far longer periods (24 to 48 hours) than conventional bougies, increasing the interval between dilatation sessions. This technique has been used several hundred times for various indications, but only 6 cases of caustic oesophagitis (with a total of 440 dilatations) each patient being followed up for more than three and a half years, have been studied in order to determine the effectiveness of the method. Amongst the causes of recurrent stenosis or of an imperfect long term result, the authors stress the role of the reflux of gastric fluid and above all of progressive fibroinflammatory mediastinitis.
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