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Biomedical subjects

J Drexler

Publications and source records attributed to J Drexler.

25 records · Page 2Linked to original sources
PubMed1974

Routine proctosigmoidoscopy: how often?

The cost-yield performance of routine proctosigmoidoscopy can be improved by far fewer examinations limited to the higher-risk patients. Since patients with diminutive polyps are at greater risk but diminutive polyps are rarely malignant and the doubling rate of colon cancer is slow, proctosigmoidoscopic examination of these higher-risk patients every 2 years is safe and more productive. Over 35 percent of those with original negative proctosigmoidoscopy demonstrate a new polyp on a second examination within 6 years. This significant shift into the higher-risk population warrants repeat proctosigmoidoscopy at least every 6 years in those without polyps.

Colonic Diseases↗
PubMedDate not supplied

Fasting plasma cyclic AMP levels in an adult diabetic and non-diabetic group.

Fasting plasma cyclic adenosine monophosphate (cAMP) was measured in 50 mature-onset diabetic patients and in 111 non-diabetic patients. Methods used to determine plasma cAMP are described. The addition of sepharose agar beads to the bovine adrenocortical binding protein has considerably improved the sensitivity and simplified the radioligand-receptor assay of cAMP. No statistical differences in plasma cAMP were noted in relation to sex in either group, to the presence of diabetes mellitus or to age or weight in the non-diabetic patients. Plasma cGMP levels are now being studied to determine if these may prove better indicators of insulin activity than plasma cAMP.

Adult↗