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Biomedical subjects

J Draeger

Publications and source records attributed to J Draeger.

At least 163 records · Page 9Linked to original sources
PubMed1983

Influence of endothelial cell count of donor's cornea on endothelial cell loss.

In an experimental study porcine corneas were trephined using different trephining procedures. For every series of trephinations, the initial cell count of the donor cornea was found to play a role in the resulting damage induced by the cutting procedure. Pretreatment of corneas and modifications of trephining conditions did not change the negative correlations between cell count and damage due to trephining.

Animals↗
PubMed1983

[Local anesthetic action of metipranolol as compared to timolol].

In a randomized study the local anesthetic side effects of the beta blockers Metipranolol and Timolol were compared. With the new electronic optical esthesiometer accurate, reproducible sensibility measurements are now possible. It can be shown that both beta blockers have a brief local anesthetic effect when applied to the cornea in drop form. There is also a relation between dose and effect.

Adult↗
PubMed1983

Visco elastic glaucoma surgery.

Hyaluronic acid facilitates and maintains separation of dissected structures in glaucoma microsurgery, thus preventing complications during surgery and in the immediate postoperative phase. Goniotomy is more easily controlled and is safer. Hyaluronic acid can therefore be used in glaucoma microsurgery to keep prepared layers of tissue separated for longer and can enlarge newly created space and almost eliminate the adhesive forces between the layers. Using hyaluronic acid the safety of glaucoma microsurgery is enhanced and the complication rate reduced. High elastic viscous substances offer better technical possibilities in microsurgery. Further experience is necessary before a final judgement can be made on the advantages.

Glaucoma↗
PubMed1982

[Long-term results after goniotomy (author's transl)].

Between 1961 and 1968 140 goniotomies were performed at the Department of Ophthalmology, University of Hamburg. The condition of 72 eyes was evaluated and 41 eyes were re-examined. The average intraocular pressure was 33 mmHg preoperativly and only 20 mmHg 13 to 20 years after the goniotomy procedure. Patients from this group with buphthalmus had an even lower pressure of only 17.6 mmHg. Pressure regulation was achieved in 85% of the evaluated eyes by one or more operations, in conjunction with drug therapy in some instances. In 18 of the 41 eyes a satisfactory result was achieved after a single goniotomy procedure. In 15 of the 41 eyes visual acuity was 0.3 or better with normal pressure. The risk of postoperative amblyopia is mentioned.

Adolescent↗
PubMed1982

[Artificial lens implantation using high-viscosity hyaluronic acid].

In implant surgery there is more damage to the endothelium than in normal cataract extraction. This damage results from the implant coming into direct contact with the endothelium during surgery. To minimize this contact, hyaluronic acid was instilled into the anterior chamber between the implant and the endothelium. The effect of this procedure post-operative endothelial cell density was investigated in a clinical study. The result was found to be a decrease in endothelial cell loss.

Cornea↗
PubMed1982

Correlations between intraocular pressure and resulting scleral indentation after detachment surgery.

The correlation of IOP, cerclage diameter and cerclage buckle height was examined experimentally for different silicone band profiles. The smallest cerclage diameter was found at the lowest IOP whereas a maximal buckle height was reached with an IOP between 10 and 15 mm Hg. For clinical application a maximal vitreous traction relief is expected with minimal IOP. The maximal buckle height in order to reach an optimal drainage barrier occurs with an IOP between 10 and 15 mm Hg.

Humans↗
PubMed1982

[Investigations under anesthesia on the effects of endogenous and exogenous factors on corneal sensitivity].

Corneal touch threshold and/or reaction time by the local anaesthetic benoxinate were determined in 91 males and females of different age groups. The corneal sensitivity decreased with advancing age, especially in the centre of the cornea. Comparing male and female subjects, the measurements of females over 40 years were significantly higher at all points of measurement than for male subjects in the same age group. In the nasal area there was a higher corneal sensitivity than in the temporal area in all subjects. Also the reaction time of equal doses of benoxinate is age-dependent meaning that the reaction time increases with age. Genetically determined differences could be supposed but are not yet certain. In order to determine that a corneal sensitivity deficiency exists, it is necessary to take age, sex and exact measurement points into account.

Adult↗
PubMed1981

[Intraocular lens implants: functional considerations, with special reference to traffic requirements (author's transl)].

High demands are made on the visual perception of individuals involved in driving, navigation and aviation. Aphakic subjects in particular may attain good central function after operation, but are subject to stringent regulations with regard to their fitness to drive, etc. Their uncorrected vision and visual fields are poor. If only one eye is aphakic there are problems especially with binocular vision. Only the implantation of an artificial lens can return the eye to a "normal" condition. Since, for many patients, driving etc. is an essential part of their occupation, there is also a social problem involved. The authors believe that such considerations justify implantation of a lens. Even where very high demands are made on function, as in the case of airline pilots, vision is fully satisfactory for traffic purposes following artificial lens implantation.

Adult↗