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Biomedical subjects

J Dorn

Publications and source records attributed to J Dorn.

25 records · Page 2Linked to original sources
PubMed1978

The manifestations, aetiology and assessment of ethanol-induced hangover.

The well-known phenomenon of hangover after ingestion of alcoholic beverages is reviewed; it appears to be due to both ethanol and congeners. Detailed studies must be preceded by the development of a system for measurement of hangover symptoms. Hangover scales are described for measurement of intensity in studies of its drug treatment. Attention is drawn to the changes in hormone levels, notably of aldosterone, renin, cortisol and testosterone in males during hangover.

Alcohol Drinking↗
PubMed1975

Influence of thyrotropin-releasing hormone on the postmenopausal female.

Daily blood samples were obtained from 5 postmenopausal patients for 21 days and analyzed for plasma follicle stimulating hormone (FSH), luteinizing hormone (LH), estrone, estradiol, progesterone, and serum T4. On days 8 through 14, oral thyrotropin-releasing hormone (TRH) was administered, 50 mg, 4 times a day. All patients showed asignificant T4 response. There was, however, no significant change in the plasma FSH, LH, estrone, estradiol, or progesterone. We conclude that oral administration ofTRH has no influence on the elevated circulating concentration of FSH and LH seen in the postmenopausal female.

Administration, Oral↗
PubMedDate not supplied

Predominance of HIV-1 subtype A and D infections in Uganda.

To better characterize the virus isolates associated with the HIV-1 epidemic in Uganda, 100 specimens from HIV-1-infected persons were randomly selected from each of two periods from late 1994 to late 1997. The 200 specimens were classified into HIV-1 subtypes by sequence- based phylogenetic analysis of the envelope (env) gp41 region; 98 (49%) were classified as env subtype A, 96 (48%) as D, 5 (2.5%) as C, and 1 was not classified as a known env subtype. Demographic characteristics of persons infected with the two principal HIV-1 subtypes, A and D, were very similar, and the proportion of either subtype did not differ significantly between early and later periods. Our systematic characterization of the HIV-1 epidemic in Uganda over an almost 3-year period documented that the distribution and degree of genetic diversity of the HIV subtypes A and D are very similar and did not change appreciably over that time.

Acquired Immunodeficiency Syndrome↗