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Biomedical subjects

J Dickinson

Publications and source records attributed to J Dickinson.

At least 19 recordsLinked to original sources
PubMed1992

Medical management of ocular malakoplakia.

A 14-year-old girl had a granulomatous conjunctival lesion, proven histologically to be malakoplakia. This is the first reported case of malakoplakia arising from conjunctiva, although three others have involved the ocular adnexa. Malakoplakia is a rare disease often associated with immunodeficiency and is characterized by the presence of intracellular inclusions and organisms due to deficient intracellular bacteriolysis. Medical management is difficult because an effective antibacterial agent requires three properties: activity against the organism involved, good intracellular penetration, and the capacity to maintain its effectiveness in the intracellular milieu. Escherichia coli was isolated from a biopsy specimen and from conjunctival swabs. Treatment with systemic ciprofloxacin, which has good intracellular penetration and activity, led to rapid resolution of the lesion. This is the first report concerning the successful use of this drug to treat malakoplakia of any organ.

Adolescent↗
PubMed1992

Delay in consulting a medical practitioner about rectal bleeding.

STUDY OBJECTIVE: The aims were to estimate the incidence of rectal bleeding in the community, and to determine the proportion of individuals who delay or fail to seek medical advice after a first episode of rectal bleeding. DESIGN: The data were collected as part of a large scale general population survey of the health practices and attitudes of individuals in a randomly selected sample of 2121 households. SETTING: The survey was conducted in the Newcastle and Lake Macquarie areas of New South Wales, Australia, during 1987-88. PARTICIPANTS: Information about rectal bleeding was collected from 1213 individuals aged 40 years and over. MEASUREMENTS AND MAIN RESULTS: Of the 1213 people aged 40 years and over, 239 (20%) reported noticing rectal bleeding at some time in their life. However, since an estimated 4.5% had noticed rectal bleeding for the first time in the past year the true lifetime incidence of rectal bleeding is likely to be much higher. Of the 77 individuals who had noticed a first occurrence of rectal bleeding more than three months but less than five years prior to the interview, 23 (30%) had either not sought medical advice or had only done so after a period of delay. The most commonly reported reason for delay or failure to consult was thinking that the bleeding was not serious and would clear up by itself. CONCLUSIONS: The data suggest that prompt investigation of rectal bleeding is not occurring in a relatively large proportion of cases. However, in the absence of firm evidence that early detection improves prognosis, and considering the costs of screening, it would be premature to initiate programmes which encourage people to seek care promptly for this symptom.

Adult↗
PubMed1992

Rural doctors.

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Australia↗
PubMed1992

Trainee research projects.

In this series, items contributed by others with research interests are welcome. This month I summarise a report presented to the 1991 RACGP convention in Hobart by Dr Roger Strasser, Senior Lecturer in Community Medicine at Monash University.

Education, Medical, Graduate↗
PubMed1991

Values and judgements of wage differentials.

This study examined the relationship between value priorities as assessed by the Rokeach Value Survey (RVS) and judgements of wage differentials. Students completed the RVS and judged the fairness of the wages for a number of jobs. Judgements of fairness were related to differences in value priorities but the justifications provided did not relate to these value priorities or draw on similar systems. The results are discussed in relation to the question of whether or not values are systematically organized, core cognitive constructs.

Adult↗
PubMed1991

My Gulf War.

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Humans↗
PubMed1990

Manual asymmetries in the reproduction of a 3-dimensional spatial location.

Two experiments examined differences in the reproduction of preselected arm positioning movements. In Experiment 1, subjects defined a position in right space with a right index finger, or a position in left space with the left index finger, and then attempted to reproduce the position with either the left or the right hand. Subjects were more accurate when vision was available and when the reproduction hand was the same as the criterion hand. Availability of vision reduced the same hand advantage. There were no accuracy differences between the left and right hands. Experiment 2 was designed to determine whether the left-left and right-right criterion and reproduction advantages evident in the no vision condition of the first experiment were accounted for by the two movements being made by the same hand or by being performed in the same space. The results demonstrated that accuracy depended primarily on whether movements were made with the same hand. No right/left hand advantage was observed. The absence of a right hand advantage in either experiment may be due to the spatial complexity of the task examined or to the relative absence of any temporal constraints.

Adult↗
PubMed1989

Bluetongue epidemiology in the Caribbean region: serological and entomological findings from a pilot sentinel system in Trinidad and Tobago.

When monitored by the agar gel immunodiffusion test for antibody to bluetongue viruses, a sentinel flock of twenty-five lambs remained seropositive through the year, whereas in a sentinel herd of twenty calves only two individuals seroconverted and these became negative again within 2 months. A light trap operated with the calf herd yielded high numbers of Culicoides insignis Lutz (over 18,000 per trap night) along with C. filariferus Hoffman, C. pusillus Lutz, C. leopoldi Ortiz, C. foxi Ortiz, C. limai Barretto, C. diabolicus Hoffman and C. guyanensis Floch and Abonnenc. Culicoides were trapped at the sheep station which had housed the lambs 3 years following the sentinel study. No virus was isolated from pools of C. insignis, C. filariferus and C. pusillus. Six other species were collected in insufficient numbers to warrant attempted virus isolations.

Animals↗
PubMed1978

Perception of blur in optometric test.

Sensitivity to blur detection was measured for 30 optometric patients by having them match the clarity [or blur] of the target words at the test endpoint with 1 of an identical set of photographically defocused words. The group showed considerable variance in their blur scores which approached a normal distribution. Some clinical implications are discussed.

Adolescent↗