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Biomedical subjects

J Dick

Publications and source records attributed to J Dick.

107 records · Page 6Linked to original sources
PubMedDate not supplied

Bacterial contamination of bone marrow grafts intended for autologous and allogeneic bone marrow transplantation. Incidence and clinical significance.

In a series of 100 bone marrow harvests, the incidence of bacterial contamination of the bone marrow graft was 17 percent. Ex vivo manipulation of some of the grafts prior to infusion may have caused additional bacterial contamination. All isolated bacteria were common skin flora, and no serious sequelae were observed in the patients receiving the culture-positive bone marrow grafts. Samples of harvested bone marrows purposely contaminated with an isolate of Staphylococcus epidermidis demonstrated a bactericidal property that was maximal early after bone marrow collection. Bone marrow collection and ex vivo manipulation may result in considerable bacterial contamination. Procedures must be developed to assure that marrow collection and processing do not result in clinically significant contamination.

Bacteria↗
PubMedDate not supplied

Anticoccidial activity of Lasalocid in control of moderate and severe coccidiosis.

The fermentation product lasalocid ("Antibiotic X-537A," Hoffmann-LaRoche) showed good anticoccidial activity when administered via feed at 50 or 75 ppm in a replicated floor-pen experiment. Lasalocid was compared with monensin (121 ppm) ("positive control") and also with unmedicated ("negative") controls in pens heavily seeded or indirectly seeded with eight species of coccidia (Eimeria acervulina, E. brunetti, E. hagani, E. maxima, E. mitati, E. necatrix, E. praecox, and E. tenella). Under severe coccidiosis exposure (litter seeded by infected birds) both anticoccidials permitted significantly increased weights, improved feed conversions, and reduced lesion scores. Shank depigmentation was numerically less in anticoccidial-treated birds than in unmedicated controls, though not significantly. Coccidiosis mortality (lesions or parasites demonstrated) was 10% in unmedicated controls. Lasaloic reduced this mortality significantly to 0.8% at 50 ppm and 0.4% at 75 ppm. No coccidiosis mortality occurred with monensin-fed birds. With moderate exposure (indirect seeding) both anticoccidials permitted significantly greater weight gains and less shank depigmentation than in unmedicated controls. In unmedicated pens severity of coccidiosis was significantly greater in the intentionally seeded pens than in indirectly seeded pens with all parameters except depigmentation. This design provided a practical procedure for testing anticoccidials in a single experiment against severe and moderate exposures to coccidiosis as are normal in broiler production.

Administration, Oral↗
PubMedDate not supplied

Magnetic stimulation of the nervous system.

Magnetic brain stimulation is a painless method of exciting cortical neurons and provides a measure of corticospinal tract function. Its clinical role is currently limited though advances in coil design may lead to wider clinical applications and to greater understanding of how the cerebral cortex functions in vivo.

Cerebral Cortex↗
PubMedDate not supplied

Asking questions.

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Decision Making, Organizational↗
PubMedDate not supplied

Educating nurse administrators.

There are startling changes occurring in the Canadian health care system as it restructures to new realities. The need for well-prepared nursing leaders has never been more evident. This article focuses on the importance of improved educational preparation for nurse administrators/executives. The authors reviewed 91 North American university calendars to determine existing educational programs. Administrators and educators must collaborate to develop educational programs that adequately prepare graduates to function within the changing health care system. To date, there is little evidence that this collaboration has taken place. In this article, the writers outline a proposed model and suggestions for a graduate education program in "nursing administration" that will meet the unique needs of today's nurse administrator/executive.

Curriculum↗