Search PubMed⌕ Search

Biomedical subjects

J Deutinger

Publications and source records attributed to J Deutinger.

143 records · Page 8Linked to original sources

[Vaginosonographic pelvimetry as a new method of the sonographic determination of internal pelvic measurements].

Up to now sonographical pelvimetry has been performed by employing compound scanners. The development of a new vaginal scanner (panorama scanner) offers the possibility of using modern real-time ultrasound equipment for pelvimetry. Measurements were performed by vaginal scanner, compound scanner and after delivery by x-ray examination in 48 patients. Evaluation of our data showed a good correlation of all three methods. In contrary to the compound scanner vaginosonographical pelvimetry is not affected by the gestational week. Furthermore this method allows also the measurement of the transversal pelvic diameter.

Female↗

[Sonographically detectable fetal epiphyseal centers as a criterion for maturity in comparison to L/S ratio].

In 62 pregnant women between the 31st and 39th week of gestation who underwent amniocentesis for determination of the lecithin: sphingomyelin ratio in the amniotic fluid, sonographical identification and measurement of epiphyseal centres around the foetal knee joint were performed. If an epiphyseal centre in the proximal area of the tibia and/or an epiphyseal centre of 6 mm or more in the distal area of the femur could be identified, this showed that a lecithin: sphingomyelin ratio greater than or equal to 2 was present. This noninvasive method of measurement of epiphyseal centres by ultrasound allows not only an exact determination of gestational week in late pregnancy, but also supplies particularly in cases of nondiabetic pregnancies, an indirect pointer to foetal maturity.

Amniocentesis↗

[Effect of induced abortion on prematurity. Analysis of the period from 1979 to 1984].

Since induced abortion is legalized in Austria the number of patients with induced abortion in their anamnesis is increasing. This factor intensified the discussion about the consequences for following pregnancies, especially the number of preterm deliveries. We investigated the influence of induced abortion on prematurity using the records of primiparae who delivered in our hospital between 1979 and 1984. Previously performed induced abortion did not affect the number of preterm-deliveries, if patients underwent early prenatal care. Patients who had their first check-up after the 18th week of gestation showed a significant increase of preterm delivery.

Abortion, Induced↗

[Changes in the diagnosis and therapy of extrauterine pregnancy].

In a retrospective study the records of all patients with proven ectopic pregnancy during the years 1971-1973 (n = 41) and 1981-1982 (n = 59) were reviewed with regard to age, symptoms, medical history, diagnostic methods, therapy, and clinical course. Particular attention was given to endocrine diagnostic methods (LH, beta-HCG), ultrasound examinations, and changes in operative therapy. The duration from admission to diagnosis of the ectopic pregnancy decreased from 5.6 to 3.3 days, circulatory shock from 32 to 10%. During 1971-1973 the fallopian tube was removed in 95%, during the years 1981-1982 only in 34%. Our study shows that modern diagnostic methods permit earlier diagnosis of ectopic pregnancy, and that in the majority of cases the removal of the fallopian tube is not necessary.

Abortion, Induced↗

[Fertility following function-preserving surgery in tubal pregnancy].

In the last few years an obvious trend toward conservative technique in tubal surgery is observed. Likewise, at our institution, emphasis was placed on preservation of function, too. 59 patients received conservative surgery of tubal pregnancies between 1979 to 1982. 7 women were lost for follow-up. 28 patients showed further desire for child-bearing. 20 of them have had a subsequent intrauterine conception (71.4%), 11 women have had term pregnancies (39.3%). 3 patients were pregnant at time of investigation. The abortion rate was 17.8%. Recurrent ectopic pregnancies were found in 5 cases (9.5%). However, the operated fallopian tube was involved only in 3 cases (5.7%). In 26 cases the patency of the tubal lumen was examined by means of hysterosalpingography. 50% of those women had remained childless. The results of HSG showed a patent passage of the operated tube in 11 cases. Our results show a high rate of subsequent pregnancies and a rather low incidence of repeat ectopic pregnancies in cases of conservative surgery and justify our decision to save the involved tube whenever fertility is desired.

Abortion, Spontaneous↗

[Intrauterine homologous insemination as a trial treatment in oligo- and oligoasthenozoospermia].

Homologous insemination, a successful treatment for subfertile couples which utilizes a new method of preparation of the ejaculate, is described. To date 264 intrauterine inseminations have been performed in 106 couples. Determination of the causes of infertility, timing of ovulation and new methods of sperm preparation are the most important factors responsible for the high rate of pregnancies. Up to now 23 of the patients treated have become pregnant (22.8%). On average, 2.5 inseminations per patient have been performed. These data represent a significant improvement on the often-used cap-method.

Adult↗

[Effect of late motility on the fertilization of ova in the IVF program].

In the course of the IVF programme at our department we made the observation that even with primarily normal sperm counts late motility often varies widely. The impression that late sperm motility might be related to successful fertilisation caused us to study the influence of late sperm motility on fertilisation rates in a series of 80 patients. Sperm was capacitated with B2 medium (Menezo INRA). Even in the presence of an originally normal sperm count, reduced late motility was associated with lower fertilisation and embryo transfer rates. It seems that late sperm motility will have to be considered as an important parameter in evaluating the prognosis for successful IVF and ET.

Adult↗

[Can fetal kidney dilatation be physiologic?].

Sonography was used to detect and to measure the foetal calyceal system in more than 100 cases of pregnancies ranging from the 25th week to term. In 13.6% of the investigated cases physiological dilatations can be demonstrated. There is no connection with the volume of the foetal bladder or with the extension of the maternal calyceal system. The observed dilatations disappear spontaneously post partum. References to pathological dilatation of the foetal calyceal system are discussed.

Diagnosis, Differential↗

[Clinical aspects and physiopathology of fetal left heart hypoplasia. 2 case reports].

2 cases of congenital hypoplastic left heart syndrome are presented with regard to clinical signs and pathophysiology. The hypoplastic left heart syndrome consists of a hypoplastic left ventricle and absence or atresia of the aortic valve, associated with severe hypoplasia of the ascending aorta and various degrees of mitral valve hypoplasia. Infants are well developed at birth but are unable to maintain sufficient circulation after physiologic closure of the ductus arteriosus.

Aorta, Thoracic↗

Immunoglobulin administration to fetuses with anemia due to alloimmunization to D.

BACKGROUND: The purpose of this study was to examine fetal tolerance of high-dose intravenous immunoglobulin (IVIG), given directly at the time of intravascular transfusion, and its effects on fetal hemolysis and pregnancy outcome in the setting of alloimmunization to D. STUDY DESIGN AND METHODS: Thirteen consecutive D+ fetuses requiring transfusion for maternal alloimmunization received high-dose IVIG (1.0 g/kg) and red cell transfusions. Twenty-four previous, consecutive fetuses with maternal anti-D served as controls. The schedules for subsequent transfusions were the same in the two groups. RESULTS: High-dose IVIG was well tolerated by all fetuses. In the IVIG group, daily decreases in hematocrit were smaller than those in controls after the second administration of IVIG (mean hematocrit decrease, 0.72 percent/day vs. 1.45 percent/day; p = 0.007). No significant difference was found in the total number of fetal transfusions, the gestational age at delivery, the duration of neonatal intensive care, the number of neonates requiring postnatal transfusion therapy, and perinatal mortality. CONCLUSION: In this small pilot study, direct administration to fetuses of IVIG with red cell transfusions was well tolerated and appeared to have a beneficial effect on fetal hemolysis.

Female↗

Twenty-four cordocenteses in one woman.

We report on 2 consecutive pregnancies in a woman with a history of neonatal death secondary to Rhesus alloimmunization. Her first subsequent pregnancy was complicated by fetal hydrops at 20 weeks of gestation. The fetus received a total of 11 intrauterine transfusions, and was delivered at 38 weeks. In the patient's next pregnancy, the fetus developed hydrops at 18 weeks of gestation. Thirteen intrauterine transfusions were given to correct fetal anemia, and a healthy baby was delivered at 38 weeks of gestational age. Continuation of intravascular transfusion therapy may represent a reasonable alternative to selective premature delivery even in cases with highly aggressive maternal Rhesus alloimmunization.

Adult↗

[Hormonal pregnancy parameters in the serum following surgery for extrauterine pregnancy].

We did serial determinations of beta-HCG, total-HCG, prolactin, SP-1, and progesterone in maternal serum after operation of an ectopic pregnancy in 38 patients. Prolactin, progesterone and SP-1 rapidly returned to normal values after removal of the ectopic pregnancy. However, the half life of HCG was related to the type of operation: after conservative operation of ectopic pregnancy the half life of HCG was greater than after tubectomy (41.4 +/- 1.9 SEM hours versus 33.4 +/- 2.0 hours), possibly due to lack of complete removal of trophoblast tissue. This fact should be kept in mind when evaluating postoperative HCG levels.

Adult↗

[Vaginal sonographic flow measurements in the uterine artery in pregnancy--advantages of the pulsed Doppler method].

Uterine artery velocimetry was performed transvaginally in 42 healthy pregnant women by means of a newly developed "panorama" sector scanner which provides a real time image of the vessel in combination with the recording of a pulsed and gated Doppler signal. Measurements were made on both uterine arteries and averaged. A/B ratios and pulsatility indices declined as pregnancy advanced. A/B ratios I. Trimenon vs. III. Trimenon = 5.44 vs. 2.20, PI = 2.59 vs. 1.32. These changes may be secondary to the conversion of spiral arteries into dilated tortuous vessels by the trophoblast invasion. Flow velocity measurements of the proximal uterine arteries provide a summery of the blood supply to all the arcuate arteries. This method will enhance our understanding of adequate placentation and may provide a new tool in the diagnosis and monitoring of complicated pregnancies.

Arteries↗

[Fetal megacystis--prenatal diagnosis and attempt at therapy].

Dilatations of the fetal urinary tract are suspect for obstructions. An extremely dilated bladder may also point to an innervation disorder. In the here presented case a very rare disease is the cause for the dilatation of the fetal bladder, the Megacystis-Microcolon-Hypoperistalsis-Syndrome. No mature ganglionic cells are detectable in the bladder wall histologically. Up to now eight cases have been reported, all female neonates died within the first days after birth. Our presented child - also a female - is now more than one year old, but artificial feeding is still necessary.

Catheters, Indwelling↗

[X chromosome recessively transmitted hydrocephalus with congenital aqueduct stenosis].

Although hydrocephalus is usually a sporadic disorder, there exist some rare but well delineated syndroms, in which recurrence is to be expected. The here presented Bickers-Adams-Syndrome of sex-linked hydrocephalus is caused by congenital aqueductal stenosis. A case of this syndrome is presented in regard to anamnesis, diagnosis, pedigree, autopsy findings and clinical management.

Adult↗

[Decrease in cerclage incidence in multiple pregnancies by vaginal ultrasound monitoring].

Cervical insufficiency is a frequent complication particularly in case of multiple pregnancy and is often considered to be an indication for cerclage operation. We performed a vaginosonographic monitoring prospectively in 35 cases with multiple pregnancy in order to diagnose cervical insufficiency early and to perform cerclage operation when indicated. The results were compared with a group of 41 patients with multiple pregnancy who received prophylactic cerclage in other hospitals. No significant difference occurred concerning the duration of the pregnancy. In patients without prophylactic cerclage the frequency of preterm contractions was significantly lower, the frequency of premature rupture of membranes, however, was higher. Our results confirm the hypothesis that the application of a prophylactic cerclage does not improve fetal outcome in case of multiple pregnancy. Vaginosonographic as a single monitoring procedure seems to sufficient for the early diagnosis of cervical insufficiency.

Adult↗