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Biomedical subjects

J Denis

Publications and source records attributed to J Denis.

121 records · Page 7Linked to original sources

Hemorrhoidectomy: Hospital Leopold Bellan procedure.

The authors describe their hemorrhoidectomy technique, a modification of Milligan-Morgan. It differs by the association of a posterior anoplasty (with internal sphincterotomy in the case of a fissure or sphincter hypertonia) and of a sub-mucocutaneous dissection of the security bridges. They report on their experience with 410 operations carried out during the year 1985. Immediate complications are mainly hemorrhage (2.68%) and urinary problems (9%). Average cicatrization time is about six weeks. At one year, there were no relapses nor fissures. A moderate stenosis was observed in 1.45% of the cases, and a hypocontinence to flatus in 2.3%. Use of a CO2 laser does not result in any modification of these results.

Fissure in Ano↗

[Efficacy of intravenous sotalol in the treatment of supraventricular tachycardia].

20 patients with supraventricular tachycardia, received one to three intravenous injections of 0.5 mg/kg of sotalol. This group included 8 atrial fibrillations, 5 atrial flutters, 2 systolic tachycardias and 5 junctional tachycardias. Return to a normal sinus rhythm is obtained in 2 of the 8 patients with atrial fibrillation while a decreased heart rate under 100 per minute is noted in 3 of them. Among the 5 patients with atrial flutter, only one returned to a normal sinus rhythm and in 2 the tachycardia decreased. In the 2 patients with systolic tachycardia, the heart rate decreased without return to a normal sinus rhythm while the heart rate decreased in all 5 cases of junctional tachycardia. A left ventricular failure with hypotension, a bradycardia at 30/min. and a transient left bundle branch block were observed during treatment. The bundle branch block is explained by an increased ventricular effective, refractory period induced by this beta-blocker. Intravenous sotalol appears as an interesting alternative in the treatment of supraventricular tachycardias with an efficacy of about 70 p. cent; it is well tolerated if the contraindications of the beta-blockers are respected.

Adult↗

[Lewis-negative blood group. Definite frequency, probable prognostic value in adult psychiatry].

The negative Lewis blood type is meaningfully more frequent with our psychiatric patients than with the general population. The theoretical interest of this fact is certain for the reason of two particularities of this blood type. It is not genetically and definitely determined at birth: the absence of passing over negativity through positivity seems to constitute a factor in favour of the blossoming of a psychiatric pathology. It is in connection with the secretory aptitude of some cells: this fact opens some perspectives for the comprehension of the deficits in the neurotransmitters. The application of theory will be confirmed by others statistics. But it indeed appears that the control of the chemiotherapy is more difficult with the negative Lewis blood type patients.

Female↗

[A peripheral biological marker of organicity. Chromosome mosaic anomalies in general psychiatry].

During February 1979 to December 1982 we studied the karyotype of 706 psychiatric adult patients without making a clinical selection. We found a chromosomial mosaïc aberration in 37 cases, concerning one leukocyte mitosis for ten studied cells : so a proportion of 5.2% cases. There do not exist statistics concerning the general population's mosaïc aberrations but in the same population the proportion of the homogeneous aberrations is near 0.5%, so 10 times lower than the proportion that we observed. The largest number of aberrations found concern the gonosomes, essentially some monosomics 45,XO or some trisomics 47,3X, among women who present a maniac depressive psychosis or another type of depression.

Adult↗

[Isolated ascites revealing a hypothyroidism. Study of 2 cases].

Ascites is an uncommon feature of hypothyroidism. We report two patients with hypothyroidism revealed by ascites. Among the 44 myxedema ascites cases found in the literature, there were observed 17 cases of ascites as the first manifestation of hypothyroidism. In this rare presentation of hypothyroidism, diagnosis is often delayed. Biological analysis of ascites usually shows high protein and cholesterol concentrations and a low or high cell count with a high proportion of lymphocytes. An increase in capillary permeability may play a role in the pathogenesis of ascites.

Aged↗