Biomedical subjects
J Deacon
Publications and source records attributed to J Deacon.
Circulating antidiuretic hormone in the human newborn.
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Emission computerised tomography. A new diagnostic imaging technique.
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Imaging: radioisotope imaging of bone.
Isotope bone scanning is here to stay: it is noninvasive, easy to perform, and economical (6 pounds per scan). The low radiation dose delivered to patients (0.03 rad/mCi to the skeleton) and the high sensitivity (less than 4 per cent of overall false positives) underline the value of this test as a screening procedure. When included in the patient's management protocol it reduces bed-occupancy time, changes the therapeutic approach to several illnesses, and substantiates general hopes that early diagnosis is the basis for progress in the treatment of benign or malignant disease.
Diagnosis of hypertrophic pulmonary osteoarthropathy.
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D-Galactonate utilisation by enteric bacteria. The catabolic pathway in Escherichia coli.
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Some properties of a pyrimidine phosphoribosyltransferase from murine leukemia cells.
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Circadian rhythms of blood pressure and pressor hormones in normal and hypertensive pregnancy.
1. Circadian patterns of blood pressure and pressor hormones were studied in late pregnancy in ten normotensive women and twenty-one hypertensives. 2. Plasma renin activity, angiotensin II and free adrenaline and noradrenaline leves were highest at 0900 h in normotensives and uncomplicated hypertensives. Catecholamine sulphate levels were lowest at 0900 h. 3. In eight pre-eclamptic hypertensives, plasma renin activity, and angiotensin II were suppressed. 4. Adrenaline sulphate levels were raised in hypertensives. 5. Four pre-eclamptics with noctural hypertension had the highest blood pressures; their diurnal rhythm for noradrenaline sulphate was reversed but they showed no consistent pattern of pressor hormones. However failure of angiotensin II, adrenaline or noradrenaline to fall at night in subjects with increased vascular reactivity could contribute to their nocturnal hypertension.
Preventing neonatal kidnapping.
Sixty-eight kidnappings of newborns were reported between 1983 and 1991 in the United States. Assessing perinatal units for areas of vulnerability and addressing identified problems can improve security. Strategies to increase the safety of neonates, including understanding the profile of the potential kidnapper, reviewing common methods of abducting infants, developing visiting guidelines, and instituting staff identification policies and other methods, are discussed.
A review of testicular intratubular germ cell neoplasia in infertile men.
A group of 2,739 infertile men whose testes were biopsied during the investigation of infertility in the period from January 1955 to December 1992 have been reviewed. Unilateral intratubular germ cell neoplasia was seen in the testicular biopsies of 16 patients and was always associated with testicular atrophy (Johnsen score lower than 4). Germ cell tumors of the testis occurred in 50% of untreated patients within 6 years and the longest period of tumor-free follow-up was 10 years. A retrospective study was performed to evaluate the incidence of tumors in a subset of 1,639 infertile men biopsied between 1955 and 1982. Three of the patients, without intratubular germ cell neoplasia on the biopsy, were found to have developed a germ cell tumor. The incidence and management of intratubular germ cell neoplasia in infertile men is discussed.