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Biomedical subjects

J Damas

Publications and source records attributed to J Damas.

At least 181 records · Page 10Linked to original sources
PubMed1976

[The hypotensive action of bradykinin in the guinea pig and cat].

In the guinea-pig as in the cat, the duration of the bradykinin general arterial hypotension is reduced by indometacine. This decrease is due to the inhibition of the synthesis of endogenous vasodilatator prostaglandins. The guinea-pig and the cat present the same type of reactivity for bradykinin as the rabbit, the dog and the rat.

Animals↗
PubMed1975

[Stimulation of the paravascular carotid receptors by bradykinin].

In the rat, intra-arterial injection of bradykinin produces either hypotension associated with polypnea or excitation with polypnea and a biphasic cardiovascular response. Intra-arterial injection of PGE, produces similar effects. Bradykinin and PGE sensitize each other. Indomethacine abolishes all vascular responses induced by bradykinin, but fails to reduce them when bradykinin is injected simultaneously with low doses of PGE. It is concluded that stimulation of paravascular nociceptive receptors is wholly responsible for the reactions by intracarotid injection of bradykinin.

Animals↗