Search PubMed⌕ Search

Biomedical subjects

J D Wicks

Publications and source records attributed to J D Wicks.

At least 37 records · Page 2Linked to original sources

Radionuclide liver and bone scanning in the evaluation of patients with endometrial carcinoma.

Staging bone scans or skeletal surveys were obtained of 97 patients with endometrial carcinoma. Of the 77 patients with Stage I or II disease, no metastases were identified at staging. Three patients in the entire series demonstrated bony metastases; all of these metastases were detectable by radionuclide bone scan and radiographic bone survey. Eighty-nine patients were examined with radionuclide liver/spleen scanning at the time of staging. Four of the 89 initial scans were interpreted as demonstrating hepatocellular disease, and all four patients had abnormal liver function studies. Only one patient demonstrated a possible hepatic metastasis at initial diagnosis. This patient also had abnormal liver function studies. Based on these results, bone surveys and radionuclide bone scans are not indicated as screening procedures in endometrial carcinoma. It is suggested that screening for liver metastases in patients with endometrial carcinoma is not warranted in patients with normal liver function studies.

Bone Neoplasms↗

Preoperative sonography of malignant ovarian neoplasms.

Patient survival in malignant ovarian tumors is directly dependent on complete surgical resection. This can be best accomplished when the surgeon is informed of tumor extent preoperatively. We retrospectively studied the preoperative sonograms of 32 patients with proven malignant ovarian tumors. Results were compared with the surgical and pathologic findings. Sonography was 97% accurate in the detection and 84% accurate in the characterization of the pelvic masses; 87.5% of these tumors were malignant by sonographic criteria. Sonography correctly staged only 48% of patients. Bowel and bladder involvement, of major importance in planning surgical treatment, were not detected by sonography. A uterus inseparable from a pelvic mass correlated with uterine involvement in 74% and this information alone may prevent laparotomy by surgeons unprepared to perform the complete resection necessary for optimum survival.

Adenocarcinoma↗

Bacterial contamination of an automated water path B-scanner.

Water path delay B-scanners are subject to bacterial contamination of the water bath. The most predominant organism has been Pseudomonas aeruginosa. To date, such contamination has not been eradicated completely. A rigid program of maintenance and surveillance is necessary to protect patients.

Pseudomonas aeruginosa↗

Biliary cystadenomas: sonographic-angiographic-pathologic correlations.

Three biliary cystadenomas are reported. Two occurred in the left lobe of the liver and the third involved the right lobe and the medial segment of the left lobe. All three patients had gray scale sonography of the liver and two underwent hepatic angiography. The sonographic features were similar to those of cystadenoma of the ovary or pancreas, that is, multilocular cystic lesions with septations and papillary projections. Angiographically the lesions were hypovascular with a faint rim of contrast-material accumulation in the wall and septa of the mass.

Adult↗

Prone-supine change in organ position: CT demonstration.

A study of positional variation of anatomic structures in 38 patients undergoing CT in both the supine and prone positions prior to beginning radiotherapy is reported. Within the thorax, turning the patient to the prone position resulted in a ventral shift of hilar structures in 36 of 38 patients. In two patients, pulmonary metastases shifted ventrally and caudally in the prone position. In all cases reviewed, prone positioning produced a ventral shift of the heart and great vessels. Within the abdomen, prone positioning produced ventral as well as caudal shift of both the liver and spleen in 34 of 38 patients. In all of the patients, a ventral shift of the kidneys as well as caudal shift was noted. Little or no variation of position was noted in cervical or pelvic structures with changing body positions.

Digestive System↗

Gas-filled appendix with meniscus: outline of the appendicolith.

A meniscus was produced in a gas-filled appendix by the outline of the obstructing appendicolith. This meniscus appearance should be specific for appendicitis since it represents the obstructing stone. This sign can be elicited by oblique or other projections, perhaps with fluoroscopic control.

Adult↗

Trophoblastic disease with coexistent fetus: a sonographic and clinical spectrum.

The sonographic and clinical spectrum of coexistent live fetus and trophoblastic disease is illustrated and discussed. Two patients with a single placenta with trophoblastic change and one patient with two placentas, one normal and one with a hydatidiform mole, are described. The clinical and sonographic abnormalities in all three patients were characteristic. In the two patients with single placenta, the histologic findings were minimal. The clinical and sonographic presentations of coexistent mole and fetus are described and etiology is discussed. The implication of the lack of histologic confirmation of hydatidiform mole suggests a spectrum of findings in trophoblastic disease.

Adult↗

Giant cystic abdominal masses in children and adolescents: ultrasonic differential diagnosis.

Twelve children and adolescents with a variety of giant cystic abdominal masses are described. These masses are easily evaluated by ultrasonic scanning. Information regarding location, size, origin, and internal structure aid in the differential diagnosis. A correct diagnosis was made in a high percentage of the cases, obviating the need for more invasive studies. Ultrasound examinations at appropriate intervals during patient management can document change in position and/or size.

Abdomen↗

Gray scale features of hematomas: an ultrasonic spectrum.

Forty-eight B-scan ultrasound examinations were performed on 25 patients with hematomas. Hematomas are usually spherical or ovoid within the abdomen, and lentiform within the pleural space or abdominal wall. They generally decrease in size with time, and usually have irregular walls. Hematomas contain a variable amount of internal echoes during the first month, and then gradually become anechoic. The sonographic appearance is not specific; an abscess may have a similar appearance. An old, anechoic hematoma may contain a gelatinous material which cannot be aspirated.

Abdomen↗

Visualization of the medullary rays on excretory urography in experimental ureteric obstruction.

Excretory urography occasionally delineates striations of alternating density in the renal parenchyma. Experimental observations on a dog model of ureteric obstruction show that the dense striations have the same dynamic alterations as the obstructive nephrogram. They become progressively more dense to a plateau and then fade with relief of obstruction. Previous obstruction is shown to facilitate visualization of the striations presumably by having dilated the tubules. Previous obstructive episode, previous symptoms, or chronic obstruction were present in each of the clinical cases collected which show a similar striation pattern. We conclude that the dense striations represent shadows produced by hyperconcentrated contrast material which has accumulated in dilated collecting ducts or groups of ducts within the medullary rays.

Acute Disease↗

Parenchymal striations in renal vein thrombosis: arteriographic demonstration.

Arteriographic visualization of parenchymal striation in renal vein thrombosis is reported for the first time. The striations correspond to the location and orientation of the peritubular capillary beds of the renal cortex, which are in linear continuity with the vasa recta of the medulla. Opacification of these vascular structures in a cadaver kidney produced the same striation pattern. One possible physiologic explanation is that renal vein thrombosis causes elevated renal interstitial pressure which slows tubular urine flow. This altered intrarenal state prevents opacification of renal tubular structures while adjacent peritubular vascular structures are opacified, thereby producing a pattern of alternating striation.

Adolescent↗

Traumatic lesions of the discovertebral junction in the lumbar spine.

Lumbar discovertebral abnormalities thought to be due to endogenous or subclinical trauma were evaluated in 22 cases. These consisted of predominantly lytic areas due to intrabody disc herniation in five cases, broad zones of vertebral body sclerosis due to reactive osteitis in 11, and destruction of the vertebral endplates surrounded by diffuse sclerosis in six. Spinal biopsy and negative bacterial cultures were consistent with the diagnosis in eight cases. Follow-up roentgenograms and further clinical evaluation in the remaining 14 showed either no progression or changes consistent with trauma. Only four cases had a history of exogenous trauma. Intrabody disc herniations usually affected the upper vertebral body with characteristic sparing of the adjacent endplate. The sclerotic lesions tended to occur in the anterior portion of the vertebral body, with the inferior aspect of L4 most frequently involved. These may be confused with osteoblastic metastases, particularly if adjacent disc narrowing is minimal. The lack of progressive vertebral fragmentation helps to distinguish this condition from neuroarthropathy. Lesions characterized by destruction of the vertebral endplates and reactive sclerosis simulate infection; absence of a soft tissue mass and clinical signs of sepsis as well as lack of progression are important differential features.

Adult↗

Co-existent renal eosinophilic granuloma and renal adenocarcinoma.

Localized renal eosinophilic granuloma has not been previously reported. In this patient there was osseous eosinophilic granuloma and a 1 cm hypervascular renal lesion which pathologically proved to be coexistent renal adenocarcinoma and eosinophilic granuloma.

Adenocarcinoma↗