Search PubMed⌕ Search

Biomedical subjects

J D Vail

Publications and source records attributed to J D Vail.

11 recordsLinked to original sources
PubMed2000

Human B-cell lines constitutively express and secrete interleukin-16.

Interleukin-16 (IL-16), produced by activated CD8+ T lymphocytes, is inhibitory to human immunodeficiency virus-1 (HIV-1) replication. In an attempt to determine whether human B cells express and secrete IL-16, a wide panel of B-cell lines derived from patients with acquired immune deficiency syndrome (AIDS)-associated B-cell lymphomas (AABCL) (n = 5) and from non-AABCLs (n = 8) were studied. Using reverse transcription-polymerase chain reaction (RT-PCR) analysis, we were able to observe ubiquitous expression of IL-16 mRNA. Kinetic studies on constitutive mRNA turnover and secretion for IL-16 suggests that the optimum expression is at 24 hr. Interestingly, we report, for the first time, IL-16 secretion by human B-cell lines.

B-Lymphocytes↗
PubMedDate not supplied

A survey of hospital AC power quality.

An AC power-quality survey was conducted at four hospitals of differing bed sizes in the Midwest. This power-line survey concentrated on determining the ac power quality in three areas: ICU/CCU, radiology, and the clinical chemistry lab. A summary of three months of monitoring indicates very stable RMS voltage levels but the presence of substantial voltage impulses or electrical noise. The substantial ac line voltage impulses observed may be of concern to both medical equipment users and designers.

Data Collection↗