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Biomedical subjects

J D Sullivan

Publications and source records attributed to J D Sullivan.

At least 19 recordsLinked to original sources

Multivariate analysis of morbidity and mortality from the initial surgical management of obstructing carcinoma of the colon.

Eighty consecutive patients presenting with complete large intestinal obstruction from primary carcinoma were evaluated. A multivariate analysis was performed to evaluate perioperative morbidity and mortality. There were five deaths in the immediate postoperative period (30 days). Extensive and lesser complications occurred in eight and 11 patients, respectively. There were 25 lesions of the right colon, whereas in 55 patients, the lesion was located distal to the left branch of the middle colic artery. Females were more likely to present with obstructed carcinomas of the left colon than males. Patients with an obstruction of the left colon more frequently presented with dehydration than those with a tumor of the right colon (p less than 0.05). Most carcinomas of the right colon were resected, whereas lesions of the left colon were managed with diverting colostomy in 33 patients and by primary resection in 22. Thirteen patients with carcinomas of the left colon had an immediate anastomosis without mortality. Preoperative severe cardiopulmonary disease, Acute Physiology and Chronic Health Evaluation score and advanced carcinoma (Dukes' C or D) were statistically related to early hospital morbidity and mortality, while individual physiologic parameters, site of lesion or operation performed were not. Primary resection may be performed safely in selected patients. Multivariate assessment and clinical staging may allow for appropriate patient selection and improve immediate outcome.

Aged

Approaches to the ankle region.

This article has attempted to address the surgical realm of the ankle region. With the advent of more interest in treating patients who require atraumatic and corrective surgical procedures of the ankle region, it is mandatory for us to become better trained and to improve our skills and expertise. The points worth summarizing in the surgical approach to the ankle region are a complete anatomic knowledge, basic principles of lines of tension, thorough understanding of biomechanics, and good preoperative judgment. The atraumatic approach was presented by describing how to accomplish this objective--by protecting neurovascular bundles, by following normal skin lines or creases, by avoiding scars over a bony prominence, and by avoiding incisions on a weight-bearing surface. Certain basic anatomic and physiologic principles were stated, such as making incisions large enough, using tourniquets when possible, avoiding excessive and unnecessary dissection, and avoiding stretching, crushing, or allowing tissue to dry. Various approaches for surgical procedures to the ankle region were given. The approaches described the location of the incision, the anatomy to be seen while deepening the wound, and the reason for the surgical procedure.

Ankle

The properties of skeletal muscle.

The authors review the musculoskeletal system and the controversy that surrounds methods for improving and strengthening it. Disorders brought on by over utilization, deficient working habits, lack of appropriate maintenance care and intercurrent stress and fatigue from repetitious daily tasks and poor sleeping habits are recognized and discussed. Also discussed are muscle structure and its relation to the contractive state, muscle energy requirements, motor control, source of muscle strength and factors modulating it, training adaptations in skeletal muscle, methods of strength training, erogenic aids including anabolic steroids and electrical stimulation and the pathologic states in muscles.

Anabolic Agents

Formation of a bone and joint following blunt injury to the pelvis.

The formation of a new bone from the lateral wall of the pelvis following blunt injury occurred in a 55-year-old woman. The bone articulated with the top of the trochanter by means of a synovial-lined joint. The case is an example of the remarkable ability of external forces to remodel newly formed bone into a functional architectural unit and to produce an accessory pseudojoint.

Bone Diseases

Calcaneal osteotomy.

The calcaneal osteotomy for the correction of valgus and varus deformities of the foot is a relatively simple and effective procedure. Since the main theme of the seminar was "Practical Reconstructive Foot Surgery," Dr. Sullivan's comments were limited to the principles of osteotomy with a brief discussion of the procedural techniques. The principles which he discusses relate to the goals to be achieved by osteotomy based on biomechanics. He also covers instrumentation, postoperative management, complications, tissue handling and choice of osteotomy sites.

Calcaneus

Sagittal hemipatellectomy in the treatment of chondromalacia patellae.

A study of the preoperative assessment, surgical technique and follow-up in 17 surgical procedures (16 patients) indicates that sagital hemipatellectomy is an acceptable alternative form of surgical treatment in patients with chronic painful chondromalacia patellae. The study series comprised 16 patient (mean age, 21 years) in whom the duration of symptoms averaged 5 years, 2 months. In all patients the procedure relieved the pain and permitted a return to their accustomed work and exercise routine within 3 to 6 months after operation. The duration of follow-up is still too short to permit evaluation of possible late complications of this procedure.

Adolescent

Factors affecting the sensitivity of Limulus lysate.

Limulus lysate clots when mixed with picogram quantities of endotoxins. The sensitivity of the lysate was improved 100-fold by the removal of an inhibitor and addition of divalent cations. The methods developed in this investigation eliminated much of the seasonable variability of the lysate, improved the heat stability after lyophilization, and made it possible to use the lysate with saline solutions.

Arachnida