The average plasma concentration of androstenedione (A) in 67 hypertensive pregnant women (mean 25.7 nmol/L, SD 10.0) was significantly higher (p less than 0.001) than that in 71 normotensive pregnant women (mean 14.2 nmol/L, SD 5.6). Androstenedione concentration decreased significantly (p less than 0.01) from this higher level with increasing gestation in pregnancies complicated by hypertension. In the normotensive group there was no significant correlation between androstenedione concentration and gestation, but a sharp increase in androstenedione concentration occurred prior to delivery. The androstenedione concentration in 18 hypertensive patients with fulminating disease (mean 30.7 nmol/L, SD 11.9) was significantly higher (p less than 0.02) than that in 49 hypertensive patients (mean 23.9 nmol/L, SD 8.7). The correlation between androstenedione and 19-hydroxyandrostenedione (19-OH-A) concentrations in plasma was highly significant; for 98 pairs, r = 0.43, p less than 0.001.

Androstenedione↗

PubMedDate not supplied

Puertitols: novel sesquiterpenes from Laurencia obtusa. Structure elucidation and absolute configuration and conformation based on circular dichroism.

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Magnetic Resonance Spectroscopy↗

PubMedDate not supplied

Teen empowerment movement to prevent tobacco use by North Carolina's youth.

Strong youth and adult leadership and exemplary policy and program interventions put a unique synergy to work in North Carolina. The state aspires to be a model for the nation in overcoming barriers related to tobacco use prevention by empowering its greatest resource--youth. New grant funding is building the foundation for youth empowerment programs, and increased and sustained funding is being sought to significantly expand these efforts. Youth speak with a fresh voice, bringing energy and conviction, as well as non-traditional ideas and strategies to the achievement of their goals. By changing public opinion and influencing the actions of leaders in the nation's leading tobacco state, the North Carolina Tobacco Prevention and Control Branch will develop leadership for tobacco use prevention that will serve the entire nation.

Adolescent↗