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Biomedical subjects

J D Manson

Publications and source records attributed to J D Manson.

At least 19 recordsLinked to original sources

Gingival inflammation and bone loss in periodontal disease.

Fifty subjects between 27 and 43 years of age were studied to determine the relationship between the severity of gingival inflammation, the amount of bone loss and the plaque score in interproximal sites. The results indicate moderately good correlations between Gingival Index or Plaque Index and percentage bone loss. However a low correlation was found between the amount of crevicular fluid and percentage loss. Gingival Index and Plaque Index were well correlated. It was also found that when patients were divided into two age groups, younger and older than 35 years, the older individuals studied had more bone loss interproximally compared with the younger despite comparable amounts of plaque or gingival inflammation. The data suggest that both severity and longevity of the inflammation may play a role in determining the rate of alveolar bone resorption.

Adult↗

Nippon journey.

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Culture↗

General anaesthesia for periodontal surgery.

A technique is described in which full-mouth periodontal surgery is carried out under general anaesthesia. The use of an endotracheal tube with inflatable cuff allows good visibility and access to all parts of the mouth unhampered by a throat pack; access is further improved by sloping the operating table foot-down. A system of haemorrhage control is used involving a combination of procedures: smooth anaesthetic induction and controlled carbon dioxide levels; intravenous injection of a fibrinolytic inhibitor (epsilon amino-caproic acid); foot-down tilt to the operating table and infiltration with local analgesic solution. The advantages and disadvantages of the technique are discussed.

Anesthesia, Dental↗

Juvenile periodontitis (periodontosis).

Juvenile periodontitis, characterized by early age of onset, rapid rate of periodontal tissue destruction and selective tooth involvement in the absence of commensurate aetiological factors, is recognized as a distinct clinical entity. The present paper describes the clinical findings and some immunological characteristics in a group of thirty-four patients under the age of thirty. Clinical aspects studied included the influence of sex, race, family history and general health. Immunological findings relating to the level of immunoglobulins in serum and saliva, lymphocyte transformation in response to veillonella, bacteroides, fusobacterium and actinomyces species and to ultrasonicated plaque, and the inhibition of macrophage migration by these antigens. Differences were shown to exist between those patients below the age of 22 years and the group aged 23-29 years.

Adolescent↗