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Biomedical subjects

J D Guin

Publications and source records attributed to J D Guin.

At least 91 records · Page 5Linked to original sources
PubMed1980

The black spot test for recognizing poison ivy and related species.

A black, enamel-like deposit is frequently present on injured areas of poison ivy, poison oak, and poison sumac. This finding can also be produced deliberately as a field test for the toxic nature of the plant. Observing proper precautions, one crushes sap from leaves onto a sheet of white paper. The resulting stain should darken on exposure to the air if it came from a Toxicodendron. This test employs only one quality of these plants, and it is not, therefore, a substitute for other proved means of identification.

Dermatitis, Toxicodendron↗
PubMed1980

Penetration of topical clindamycin into comedones.

Comedones were removed from patients on topical clindamycin and assayed for that antibiotic by of two methods. Prominent levels were found in eight of ten patients by one bioassay method. Once whole comedones from a patient were found to be positive, other comedones were microdissected to separate the external and internal portions. Prominent levels of clindamycin were found in the inner portion as early as 2 weeks. Further, the antibiotic could always be found in the internal portion when it was present in the external layers. Using the more sensitive of two bioassay methods, the whole comedonal level of clindamycin ranged from 0 to 5 microgram/mg of comedonal material, with an average level of 0.824 microgram/mg. The significance of this is discussed.

Acne Vulgaris↗
PubMed1980

Bullous hemorrhagic eruption: a drug-induced disease.

A case is reported of bullous hemorrhagic eruption associated with furosemide. The condition represents a drug-induced vasculitis which presents clinically as a striking purpuric eruption with multiple tense subepidermal bullae. The typical clinical findings, the course of the eruption and negative or nonspecific immunofluorescent findings are distinctive enough to consider this a specific entity.

Aged↗
PubMed1980

Alopecia areata.

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Alopecia Areata↗
PubMed1980

Perfume sensitivity in adult females. A study of contact sensitivity to a perfume mix in two groups of student nurses.

The incidence of contact sensitivity to a perfume mix was investigated in two groups of student nurses by questionnaire and patch testing. Twenty-nine of ninety gave a history of dermatitis on exposure to fragrances or perfumed cosmetics. Fifteen of eighty-five showed a positive patch test reaction to a perfume mix comprising 2% concentrations of eight different perfume ingredients, and twelve of the fifteen had a positive history. Chi-square analysis of the data indicates that the results of the two methods of measurements are significantly related (p < 0.0001).

Dermatitis, Contact↗
PubMed1979

Yellow nail syndrome. Possible association with malignancy.

A dramatic resolution of yellow nail deformity occurred in a 66-year-old man shortly after the removal of a carcinoma of the larynx. Seventeen months later, a productive cough developed and radiologic evidence of bronchiectasis was found. There was no evidence of lymphedema, pleural effusion, sinusitis, or immunologic abnormalities. At least three other patients with a variant of yellow nail syndrome have died of malignancy. Therefore, the resolution of the nail deformity following laryngectomy may not be fortuitous.

Aged↗
PubMed1979

Decubitus ulcers.

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Dextrans↗