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Biomedical subjects

J D Adams

Publications and source records attributed to J D Adams.

At least 145 records · Page 8Linked to original sources

Cytological effects of phenothiazine tranquilizing agents on barley meristems.

A growth reduction of 30--40% was noted in barley plants grown in two phenothiazine tranquilizers. Similar reductions were noted in the number of mid-anaphase cells, indicating the reduced growth could have been the result of a reduced mitotic rate. Also observed were several types of chromosomal aberrations. Electron microscopy revealed less endoplasmic reticulum and cytoplasmic organelles in the treated cells than in untreated cells. Various sized discontinuities in the nuclear membrane was the most frequent abnormality observed in the electron micrographs. The abnormal nuclear membrane was possibly a result of enzyme degradation.

Antipsychotic Agents↗

Worker environment research. IV. The effect of dust derived from several soil types on the dissipation of parathion and paraoxon dislodgable residues on citrus foliage.

Parathion sorbed to dust can persist as dislodgable residues on citrus leaves. Semi-logarithmic plots of parathion dislodgable residue data were initially linear for the 6 soils studied and then a distinct change to lower rates occurred with 5 of the soils. As initial rates and the residue level at the rate change are dependent on the soil, foliar dust is implicated as a causative factor in the non-uniformity of residue dissipation rates. Soils can influence the conversion of parathion to paraoxon. Paraoxon levels differed greatly with the type of soil and were highest with Pike's Peak clay. Thus, its use in a parathion formulation could produce relatively high levels of paraoxon dislodgable residues. It is significant that, second to Pike's Peak clay, the highest total dislodgable residue level was found with Visalia silt loam which was collected from a grove where a worker poisoning episode had occurred in 1974.

Adsorption↗

Growth effects of tranquilizing agents containing phenothiazine derivatives on barley seedlings-1.

Two prescription tranquilizers reduced the growth of barley plants by as much as 50%. Measurements of the long axis of mid-anaphase cells from shoot meristems did not seem to explain the reduced growth. However, observations from electron micrographs indicated abnormal nuclear membranes would not undergo the usual mitotic divisions which, in turn, could account for the reduction in growth. Futhermore, it is suggested that the opening of the nuclear membrane resulted from enzyme degradation.

Cell Division↗