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Biomedical subjects

J Cukier

Publications and source records attributed to J Cukier.

At least 91 records · Page 5Linked to original sources
PubMed1983

[Accidental urethral rupture during coitus].

Emergency surgery in three cases of accidental urethral rupture during coitus involved suture of the tunica albuginea corpus cavernosum and immediate repair of the urethra under cover of a urethral guide and a cystostomy. The three perfect results obtained, with normal micturition and more particularly normal erections, together with data from reports in the published literature, strongly suggest the need for urgent repair of traumatic lesions of the corpora cavernosae during coitus. The possibility of a urethral rupture makes urgent operation even more essential, before the patient urinates, to avoid transformation of a traumatic hematoma into a urohematoma.

Adult↗
PubMed1983

[Epididymo-deferens anastomosis. Experimental study in the rat].

Fifty Wistar rats underwent right epididymo-deferens anastomosis by microsurgery, 1 to 4 weeks after ligation of the right epididymo-deferens loop. The left testis was removed in the first 32 rats. The others also underwent anastomosis but without prior ligation. Amongst the 25 rats now studied by mating, vaso-epididymography and dye injection, we have found 14 obstructions, 5 cases of permeability without fertilisation and 6 fertile and permeable animals. This series demonstrates for the first time the possibility of success of such anastomosis in the animal. They are designed to replace the classical latero-lateral anastomosis. The latter causes a spermatic granuloma by epididymal fistula. Recanalisation of the granuloma explains the frequency of postoperative oligospermia in patients with normal testes. The first results in man are very encouraging.

Animals↗
PubMed1982

[Extravesical openings of ectopic ureters: diagnostic problems (author's transl)].

The authors have reviewed 80 cases of ectopic ureter in 74 patients (62 women and 12 men). In most cases the abnormality involved the upper part of a double ureter system, and the extravesical openings were not only ectopic (located within or, most commonly, below the vesical sphincter in women), but also malformed with stenosis and/or reflux. The kidneys drained were damaged by dysplasia and/or interstitial nephritis. The presenting symptoms were fever, abdominal pain and disorders of micturition; incontinence, exclusively found in women, took only second rank. The purulent urine discharged could pass for leucorrhoea. Diagnosis was made by intravenous urography and by clinical or endoscopic finding of the ectopic opening.

Female↗
PubMed1982

Simultaneous posterior and anterior interosseous nerve syndromes.

A patient with simultaneous posterior and anterior interosseous nerve syndromes is presented. During induction of anesthesia, the paralyzed muscles exhibited denervation sensitivity to succinylcholine. Following exploration and repair of a posterior interosseous nerve defect, full function returned in the dorsal muscles as well as the flexor pollicis longus and pronator quadratus muscles.

Adult↗
PubMed1982

[Transurethral resection of the prostate (author's transl)].

The authors report a retrospective study of 320 primary resections for benign prostatic hypertrophy yielding a mean weight of 30 grams, only 5% exceeding 50 grams. Routine internal urethrotomy of the penible urethra carried out in 62 patients did not prevent urethral stenosis in 2 of them. There were no cases of fluid absorption syndrome, but the relatively frequent nature of the immediate (5 cases) or early (10 cases) abundant bleeding should be noted. Only one third of the patients required a transfusion. Seventeen developed a septicaemia and six epididymitis. Septicaemia (2 cases), pulmonary embolism (1 case) and cardiac insufficiency (1 case), were the causes of the 4 deaths (1.25%). There were 14 cases of urethral stenosis, 19 of incomplete resection, 1 fibrosis of the prostatic bed and 6 fibrosis of the bladder neck. There were 3 cases of complete incontinence (0.9%). In this retrospective series, spread over 7 years and involving 16 different surgeons, 80% of the patients undergoing resection had a perfect result, to which could be added 7%, following minor endoscopic re-operation for urethral stenosis or incomplete prostatic resection. The experience of the surgeon and the improvements in equipment appeared to be the two essential factors in the improvement of results of endoscopic resection for benign prostatic hypertrophy.

Humans↗
PubMed1982

[Complete retention of urine of sudden onset secondary to herpes genitalis infection (author's transl)].

The authors report three cases of complete urinary retention of sudden onset during a herpes genitalis infection secondary to traumatic sexual relations. In practice, the diagnosis was made in the absence of any urological cause, the presence of local signs indicative of herpetic infection of the genital organs and lumbar puncture. Mictional disturbances disappeared in 2 to 3 weeks without leaving any sequelae. The possibility of nervous system complications in genital herpes infections has been know since 1904. By contrast, disturbances in micturition have been reported much more recently, in 1953. Complete urinary retention of sudden onset is not rare: 17 cases out of a series of 486 cases of genital infection. This may be the only clinical sign of nervous system involvement. Urinary retention develops between a few days and 3 weeks after the onset of genital herpes. Neurological examination of the lower limbs is normal. There may be transient impotence in the male and loss of the bulbo-cavernosus reflexes and impaired sensation in an S2-S3 distribution. Bladder tone is spontaneously hypoactive and increases following the injection of Urecholine. The herpes virus (HSV) is found only during the acute phase of the genital infection but almost never a few days later, when urinary retention develops.

Antibodies, Viral↗
PubMed1982

[Diagnosis, prevalence, prognosis and treatment of the trophoblastic component in germinal tumours of the testis in the adult].

The authors report a series of 97 germinal tumours of the testis in the adult, studied first in terms of conventional histological data. Of 33 seminomas, 2 secreted HCG. The 5-year actuarial survival at stage I was 93%, and at stage II 75%. Stage II deaths revealed the existence of not purely seminomatous tumours. Amongst dysembryomas, half secreted HCG, with 3 histological groups: predominant choriocarcinomas, tumours with a trophoblastic component and "apparently pure" dysembryomas. The 3-year actuarial survival for dysembryomas was 90% at stage I and 58% at stage II. 51 patients of the series were studied retrospectively by sections with HCG peroxidase, a technique which reveals the intracytoplasmic synthesis of the hormone. Two types of cells have proved capable of such synthesis: syncytial cells, of syncytial-trophoblastic type, and small mononuclear cells. One third of seminomas and 90% of dysembryomas proved to have a trophoblastic component as demonstrated by HCG immunoperoxidases. All patients secreting HCG were HCG peroxidase positive. This equally applied to all patients with syncytial cells. Furthermore, all the indications are that HCG secretion is above all by the syncytial cells. From a diagnostic standpoint, any rise in beta HCG is synonymous with an HCG immunoperoxidase trophoblastic component. Detection of such a component using immunoperoxidase would seem to be essential for non-secreting tumours. From a prognostic standpoint, seminomas with a trophoblastic component are in fact dysembryomas and lymph node dissection should be performed, this being the only way of not missing a non-seminomatous metastasis. Therapeutically, pure seminomas are distinguished by the possibility of cure by radiotherapy. For all other tumours, orchidectomy must be followed by lymph node dissection. Subsequent treatment is decided on the basis of the results of the latter, with the exception of tumours with visceral metastases where chemotherapy must come first.

Adult↗
PubMed1982

[Triamterene induced nephrolithiasis (author's transl)].

Various studies have demonstrated a relationship between nephrolithiasis and the ingestion of certain drugs. We are particularly interested in the effects of triamterene. Five published case studies on patients of both sexes between 43 and 60 years of age have proven that a regular consumption of normal doses of triamterene has a direct effect upon the formation of renal stones. The stones analysed by infra-red spectrophotometry during the above observations contained from 20 to 100% of triamterene and it's metabolite hydroxytriamterene, following a daily consumption of 150 to 350 mg during a period of 6 to 38 months. It has been confirmed that triamterene and it's metabolite hydroxytriamterene are very poorly soluble and super-saturate the urine for a brief period following the ingestion of the drug. Triamterene might also intervene in the initial phenomena of nucleation. It is therefore recommended that triamterene be used with caution in those patients presenting a history of nephrolithiasis. The existence of drug induced nephrolithiasis reinforces the importance of the technique of renal stone analysis, and the necessity of a systematic study of all renal stones found. This will allow us to develop the study of the correlations between the different episodes of renal stone disease, the nature of the treatment undertaken and the systematic analysis, layer by layer, of the stone.

Adult↗
PubMed1982

[Comparative experimental study of the renal consequences of vesico-ureteric reflux and of ureteric obstruction in the sheep foetus (author's transl)].

The authors sought to determine what links existed between foetal vesico-ureteric reflux and renal dysplasia. Using sheep with operation upon the foetuses in utero, at a fairly early stage of gestation, the following were obtained: 1) Foetal vesico-ureteric reflux by unilateral excision of a ureteric meatus. 2) Stenosis of the foetal ureter by ligation. In the first case, no renal dysplasia occurred. In the second case, dysplasia-type parenchymatous lesions were found. This led them to conclude that the direct relationship between isolated foetal vesico ureteric reflux created experimentally in a normal ureter (without any additional functional or organic obstructive factor) and renal dysplasia could not be demonstrated in the sheep foetus.

Animals↗
PubMed1982

Augmentation mammaplasty: a review of 18 years.

We have reviewed the experience of our clinic since 1962, when the first augmentation mammaplasty using a silicone implant was performed. All-inclusive, this review of 1,567 patients has taken us through a metamorphosis of improved prostheses and refined surgical and postoperative techniques that have resulted in a significantly lower incidence of breast firmness. Since the purpose of all aesthetic surgery is to improve the quality of life of the patient through an enhancement of her or his own self-image, the results of present-day augmentation mammaplasty with the Silastic gel prosthesis indicate that this surgery is worthwhile and should be continued. It is anticipated that further improvement in results will be noted when the problem of subclinical infection is resolved.

Breast↗
PubMed1982

[The role of foetal surgery in urology (author's transl)].

The authors report a brief experimental study showing that cystostomy performed in utero perfectly prevents, at least in the animal, deterioration of the urinary tract after urethral ligation. In the light of this experimental finding, the authors raised the question as to whether there is not a place for such bypass urinary surgery in utero in the humans. Indications would be highly obstructive forms of valves of the posterior urethra, treated in utero by cystostomy and, secondly, severe obstructions of the excretory system which could be temporarily bypassed by pyelostomy. This risks are described, but the possibility of such surgery is not excluded.

Animals↗
PubMed1982

[Teratoma of the renal sinus. Apropos of a Case].

The authors report a new case of teratoma of the renal fossa. Such tumours are rare. The case reported is unusual since it involved an older child and because the small lesion was located in the renal sinus and not in the parenchyma.

Child↗
PubMed1982

[Adjuvant chemotherapy in the treatment of infiltrating cancers of the bladder. Preliminary results in 25 cases].

Twenty-five cases of invasive carcinoma of the bladder treated by surgery, radiotherapy and chemotherapy are discussed. Cis-diammine dichloroplatinum (CDDP) was used in 8 cases, bleomycin in perfusion in 6 cases and a combination of CDDP and adriamycin in 11 cases. Of 8 cases with lymph node invasion, 4 are alive 5 to 21 months after the start of treatment. Of 12 who were followed up and has no nodal involvement, 9 are alive 5 to 52 months from the start of treatment. The tolerance to treatment is poor, but the results are encouraging. Therefore, we suggest a program of treatment consisting of intense preoperative radiotherapy, partial or radical cystectomy, followed by an combination of 100 mg of CDDP and 60 mg of adriamycin monthly for 9 months.

Aged↗