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Biomedical subjects

J Cuevas

Publications and source records attributed to J Cuevas.

At least 55 records · Page 3Linked to original sources
PubMed1989

[Is it possible to relate reflux esophagitis to epidermoid carcinoma of the esophagus?].

The authors present a retrospective study of 120 cases of epidermoid carcinoma of the esophagus, in which they proposed to investigate the etiopathogenic relation between gastroesophageal reflux and noplastic development. A statistically significant relation was found between esophagitis and cancer of the distal esophageal third, indicating the need for vigilance of patients with reflux and for randomized prospective studies to clarify the problem definitively.

Adult↗
PubMed1989

[Superficial gastric carcinoma. Clinical analysis].

While in Japan the incidence of superficial gastric cancer (CGS) is very high (35%), with a mean 5-year survival rate of 95%, in our environment it is infrequent. Although the global incidence of gastric cancer is declining, recently, since endoscopy became routine, an increase has been seen in the diagnosis of superficial gastric cancer. In the period between 1976-1982 two cases were diagnosed in our service, but between 1982-1986 the total number of cases found was 23, representing 0.37% of all the endoscopies performed (approx. 6,800) and 8.6% of those diagnostic of gastric cancer (266 cases). Of the lesions, 60.8% were located in the antral region and the most common accompanying symptomatology was ulcerative syndrome (47.3%). The predominant tumoral type was ulcerative (73.9%) (classification of the Japanese Endoscopy Society). The benefits of radiological study were nil, while endoscopic biopsy was diagnostic in 100% after an average of 1.8 (1-4) endoscopies per patient with 6-12 biopsy samples obtained in each endoscopy. Of these 23 patients, 8 underwent total gastrectomy, 14 partial gastrectomy and one refused surgical treatment. The survival was 91.3%, with a follow-up of 6 to 60 months, and two deaths were due to nontumoral causes.

Adult↗
PubMed1987

Psychophysiological correlates of induced headaches.

The psychophysiological correlates of induced headaches were examined. Subjects with frequent muscle-contraction headaches, frequent migraine headaches, or infrequent headaches were exposed to a 1-h cognitive stressor while multiple electromyographic and cardiovascular measures were monitored. The stressor was associated with significant changes in all psychophysiological measures. Eleven of 16 headache subjects and 2 of 8 control subjects developed headaches. Significant associations between several psychophysiological variables and headache occurrence were found and individual differences in the association between psychophysiological variables and headaches intensity were examined. The results were consistent with the hypothesized role of cardiovascular factors in the pathophysiology of muscle-contraction headache. This was the first controlled demonstration of headaches occurring as a function of environmental stressors.

Adolescent↗
PubMed1987

[Calcifications in leukokorias: ultrasonic study].

We have performed an ultrasound study of 46 eyes with Leucocoria. The results obtained demonstrate that 20 eyes (43.5%) were affected by retinoblastoma. Of these, 17 eyes (85%) showed calcifications and 3 eyes (15%) did not show calcifications. In the remaining 26 eyes, in 6 cases there were intraocular calcifications, and in two of these the calcifications were found within the pathological intraocular mass showing retinoblastoma. The eyes with intraocular calcifications were diagnosed as: uveitis, retrolental fibroplasia, Coats disease, retinal dysplasia. Because of these, we conclude that, although the existence of calcifications is a meaningful datum, there are uncalcified retinoblastomas and calcifications in entities other than retinoblastoma.

Calcinosis↗
PubMed1987

[Wolman's disease].

We present two brothers with Wolman's disease under its child form. Adrenal calcification, a diagnostic suspicion sign, was present in the second brother only. Vacuolated cells in bone marrow and intestine villi shown in pathological study, and cholesterol crystals in Kupffer cells were determinative. Acid esterase (0.85 nmol/mg/m) in fibroblast culture in the second brother was pathognomonic (normal values: 30 nmol/mg/m). Enzymatic values in parents were normal. Evolution in both cases was to early death, five and eight months respectively. Enzymatic study in amniotic cells culture over fifteen week of a third bearing was normal.

Acetylesterase↗
PubMed1985

Enhanced adverse electrophysiologic effects of histamine after myocardial infarction in guinea pigs.

To evaluate the electrophysiological sensitivity of infarcted myocardium to histamine, we used microelectrodes to study its effects in isolated guinea-pig left ventricles 1 hr (acute), 24 hr (subacute) and 4 to 6 weeks (chronic) after multiple (6-8) ligations of the left coronary artery system. In both control and infarcted preparations, histamine (10(-8) to 10(-5) M) caused marked concentration-dependent increases in automaticity. Histamine also induced rhythm disturbances, including premature depolarizations, irregular patterns of spontaneous depolarization and spontaneous bursts of rapid ventricular activity. In each case, threshold concentrations for these effects were lowest in the preparations with infarcts. Cimetidine (10(-5) M) abolished the arrhythmogenic effects of histamine, whereas chlorpheniramine (10(-5) M) did not; beta adrenergic blockade induced by propranolol also had no effect. The effects of histamine were mimicked in normal hearts by the H2-agonist dimaprit. These data indicate that threshold concentrations of histamine induce rhythm disturbances in the setting of experimental myocardial infarction. We suggest histamine plays some role in arrhythmias associated with myocardial infarction in humans.

Action Potentials↗
PubMed1983

Cyst of accessory lacrimal gland.

We present a case of an epithelial cyst of the conjunctiva caused by the dilatation of an accessory lacrimal gland. The case is peculiar in regard to the size of the cyst and the absence of traumatic or inflammatory factors to explain the retention of fluid.

Adult↗