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J Cseh

Publications and source records attributed to J Cseh.

16 recordsLinked to original sources

Isolation, structure and properties of the C-terminal flanking peptide of preprocholecystokinin from rat brain.

The C-terminal flanking peptide of preprocholecystokinin has been isolated from rat brain. Micro-sequence analysis revealed the primary structure: Ser-Ala-Glu-Asp-Tyr-Glu-Tyr-Pro-Ser. Arylsulphatase and mild acid hydrolysis suggested that both tyrosine residues are sulphated. The peptide was not active in bioassay systems that respond to CCK8; the significance of the conserved tripeptide Ser-Ala-Glu is discussed.

Amino Acid Sequence↗

Urinary beta 2-microglobulin and retinol binding protein: individual fluctuations in cadmium-exposed workers.

Urinary retinol binding protein (RBP) and beta 2-microglobulin (beta 2-m) were compared in apparently healthy population groups with and without occupational exposure to cadmium (Cd). The relationship observed in neutral urine was: RBP (micrograms/mmol creatinine) = 0.786 + 0.814 beta 2-m (micrograms/mmol creatinine). This relationship was similar to that reported for patients with various renal diseases [13]. Analysis of urine samples collected weekly from workers exposed occupationally to Cd revealed marked fluctuations, not only in the concentration of the acid-labile beta 2-m but also in the level of the pre-analytically more stable RBP. Therefore, repeated sampling and urine analyses are suggested as means to obtain more reliable data when monitoring Cd-exposed personnel.

Aged↗

12C

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Journal Article↗

Enzyme induction by o-xylene inhalation.

Inhalation of 4500 mg o-xylene by rats was found to produce adaptational and pathologic changes in the liver by the end of the 1st week, reflected in an increase in relative liver weight, shortening of the hexobarbital sleeping time, an increase in the concentration of cytochrome P-450, with a decrease in the activities of aniline hydroxylase and of aminopyrine N-demethylase. Six weeks after the start of inhalations all the changes in the liver and in the mixed function oxydase system (MFO) were of an adaptational pattern characterized by an increase in relative liver weight as well as in cytochrome P-450 and b5 concentrations, a shortening of the hexobarbital sleeping time and an increase in the activity of aniline hydroxylase and of aminopyrine N-demethylase.

Adaptation, Physiological↗