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Biomedical subjects

J Cox

Publications and source records attributed to J Cox.

At least 253 records · Page 14Linked to original sources
PubMed1979

Identification of a lobe in the adult human pancreas rich in pancreatic polypeptide.

Systematic sampling of human necropsy pancreases has revealed that pancreatic polypeptide (PP) cells are not distributed equally in the gland. PP-cells are the most abundant cell type in the posterior part of the pancreatic head while they are scarce or absent in the remainder of the gland. The PP-rich part of the head can be separated by blunt dissection from the pancreas as a discrete lobe. This lobe probably originates from the ventral pancreatic bud during embryogenesis. A quantitative study of the immunofluorescent endocrine cell types (insulin, glucagon, somatostatin and pancreatic polypeptide cells) in PP-rich and PP-poor regions of pancreases in 8 subjects with ages ranging from 33 fetal weeks to 80 years, showed that the proportions of the cell types were different in youngs and adults.

Adult↗
PubMed1979

Maternal attitudes toward circumcision.

Two hundred questionnaires were completed anonymously by mothers to determine the nature of their attitudes and knowledge of neonatal circumcision. Neonatal circumcision had been performed on 95 percent of the sons. A wide variety of reasons were given for circumcising newborns; few were medically valid. Eighty-seven percent of mothers considered circumcision to be without risk, and 80 percent of mothers stated that the risks of circumcision had not been explained to them. This retrospective study revealed a lack of maternal understanding regarding neonatal circumcision.

Adult↗
PubMed1978

Radionuclide imaging of Meckel's diverticulum in children.

Fifty-eight children were studied for the presence of Meckel's diverticulum by scintigraphy with 99mTc-pertechnetate. Meckel's diverticulum was found at surgery in 6 of 6 patients with positive radionuclide studies and in 2 of 48 patients with negative studies. Four studies could not be interpreted because of widespread intestinal activity. Using the criteria described in this paper, false-positive readings did not occur.

Adolescent↗
PubMed1978

[A case of endothelial splenic cyst in an infant].

The authors report a case of isolated splenomegaly in a healthy 7-year-old boy, not showing any other clinical or biological anomaly. The radiological examination (selective arteriography of left renal artery) and spleenscan were compatible with an intrasplenic process. The splenectomy was performed. The spleen was large (15/20 cm) and demonstrating a cystic lesion in the inferior pole. Histological examination revealed polycystic formations covered with endothelial type cells and associated with angiomatous multifocal lesions. Differential diagnosis of cystic lesions of the spleen is discussed and complete preoperative investigation is stressed.

Child↗
PubMed1977

Clinical report of the treatment of locally advanced lung cancer.

This paper discusses the results of the treatment of 345 patients entered in the Veterans Administration Lung Group Protocol 13L. The study was activated March 1972, and closed for the patient accesion March 1975. All patients had a histological diagnosis of primary lung cancer considered clinically non-resectable or inoperable. Patients were equally randomized into two groups, radiotherapy alone or radiotherapy with chemotherapy. The analysis of the data included: treatment regimen, radiation dose, initial performance status, performance status change, cell type, duration of survival, quality of survival and age. The strongest influence on median survival was the level of radiation dose. The small cell carcinoma patients treated with radiotherapy and chemotherapy showed significant improvement in the median survival (38.2 weeks) over the patients treated with radiotherapy alone (20.6 weeks). The patients treated with radiotherapy and chemotherapy also showed improvement in performance status more frequently than the patients treated with radiotherapy alone. Other parameters of the analysis will be presented.

Adenocarcinoma↗