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Biomedical subjects

J Couvreur

Publications and source records attributed to J Couvreur.

At least 55 records · Page 3Linked to original sources
PubMed1983

[Legionella pneumophila pneumopathy in a 4 1/2-month-old infant].

A 4 1/2 month-old infant presented with severe alveolo-interstitial pneumonitis needing intubation and mechanical ventilation. Legionella pneumophila infection was established by a significant increase in antibody titers. The clinical picture was consistent with that of legionnaires' disease. No immune defect could be proven.

Female↗
PubMed1983

[Pneumopathies caused by Chlamydia trachomatis in pediatrics].

Chlamydia trachomatis now has an important place in infantile respiratory pathology. In neonates, it is transmitted in utero, which explains one quarter of the cases of interstitial pneumonia seen during the first months of life. In children, the number of carriers of antibodies increases with age and may be more than 40 p. cent by the age of 7 years. The mode of contamination and the pathological significance remain uncertain in this age group. Chlamydia trachomatis can be a cause of pneumonia in immuno-depressed patients. A survey conducted in a Paediatric Respiratory Medicine Unit showed that 22 p. cent of patients were carriers of the antibody and at least 7.8 p. cent were infected.

Adolescent↗
PubMed1980

[Interstitial pneumonia due to Chlamydia trachomatis in infants. Three cases (author's transl)].

The early onset of the disease (between the 13th and 15th days of life) and its long duration in 2 out of 3 cases, the absence of infectious symptoms and the efficacy of erythromycin treatment were characteristic features. The diagnosis was confirmed by positive (greater than 1/32th) serological tests in both infants and parents. Chlamydia trachomatis lung infection should be suspected in infants presenting, during the first weeks of life, with cough and dyspnoea unaccompanied by fever, radiological evidence of interstitial pneumonia, blood eosinophilia and raised immunoglobulin levels. The disease results from intranatal contamination and might represent, in France as in the U.S.A., an important percentage of respiratory infections occurring during the early months of life.

Chlamydia Infections↗
PubMed1979

[Diagnosis of interstitial pneumopathies in infants (author's transl)].

The authors discuss the etiological features of interstitial pneumopathies, with particular emphasis on their characteristics in the newborn and in immunodeficient children, and review the diagnostic findings : clinical and radiological signs, functional disturbances, and results of pulmonary biopsy. The results of 154 needle biopsies in 124 children aged 1 month to 16 years are described. In 103 cases a diffuse pneumopathy was present and 80 % of the biopsies were successful. Precise diagnosis could be made from the histology specimen in 22 cases out of the 82 examined, while in 60 of these cases the specimen could be identified.

Adolescent↗
PubMed1979

[Results of lung biopsy in interstitial pneumopathies in children. A report on 100 cases (author's transl)].

Needle biopsy was performed in 100 children with diffuse interstitial pneumopathy. Severe histological lesions were noted in the biopsy sections in 4 out 5 cases. Those most frequently observed (57 cases) were non-specific lesions of diffuse interstitial pneumopathy (DIP) or idiopathic fibrosis, the course of which was followed, in some cases, by repeating the biopsy. Specific lesions, especially idiopathic pulmonary hemosiderosis (8 cases), were noted in 22 children, either associated with interstitial fibrosis or apparently better tolerated. The other 16 cases included the lipoidoses (Niemann-Pick, histiocytosis X), alveolar microlithiasis, and some specific inflammatory diseases (tuberculosis, syphilis) or those related to inhalation of a foreign body.

Adolescent↗
PubMed1977

[Inappropriate secretion of ADH during acute respiratory infections due to adenovirus in children (author's transl)].

Four children aged between 7 and 19 months with severe bronchopneumonia due to adenovirus type 7, proved by virology and/or serology developed severe hyponatraemia. One of them is reported in detail: it was possible to estimate plasma ADH levels and thereby prove the existence of reversible hypersecretion of the hormone. Whilst the syndrome of hyponatraemia with inappropriate secretion of ADH has not yet been reported in association with severe pneumonia in the child, it is known in adults. The limits of the syndrome and its physiopathology are discussed. It may be due either to vagal stimulation as a result of a fall in left aressure, or to central involvement. Therapeutic implications of the problem are emphasized.

Adenoviridae Infections↗