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Biomedical subjects

J Costa

Publications and source records attributed to J Costa.

336 records · Page 19Linked to original sources
PubMedDate not supplied

[Three years of AIDS. Experience of the Curry Cabral Hospital with HIV infections (1985-1988)].

The AA. present a retrospective study on their experience with HIV positive patients, followed on the Infectious Diseases Department of the Hospital Curry Cabral, in Lisbon. This study was done in 90 patients seen since 1985 till March 1988. From the 90 patients, 81 were HIV--1 positive, 6 HIV--2 and 3 HIV1 + HIV2 positives. It is presented their distribution by sex (Male = 97.8%), age (mean--36.5 years), risk groups (homosexuals--64.4%, heterosexuals--21.1%, IVDA--7.7%, blood-related--5.6%), and their Walter Reed and CDC classifications. It is emphasised the increasing incidence of infected people along the years and an unexpected high rate of heterosexual males infected. It is also pointed the incidence of Kaposi (22%), Pneumocystis carinii pneumonia (55.6%), and Criptococosis (13.9%) in the WR6 group. The mortality rate was 31.3% for WR5 and 63.9% for WR6. We calculate some Relative Risks for clinical situations matched with risk groups and immunological status (meaning the T Helper lymphocitic count), and measured their statistical significance with the chi-square test. Besides the immunodeficiency, it was mentioned the associated lymphadenopathy and dermatological lesions, the HIV encephalopathy and the constitutional symptoms of the wasting syndrome.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

[The international project of healthy cities: conceptual basis and perspectives for its development in Spain].

The authors present the conceptual foundations of the international Healthy Cities project of the European Office of the World Health Organization. The future of municipal public health services in Spain after the General Health Act of 1986 is discussed, since it plans the integration of all health services in the public sector within a National Health Service. In this context, the potential to develop health promotion initiatives from the local government is discussed. The objectives and development of the Spanish Healthy Cities network are also presented.

Health Promotion↗
PubMedDate not supplied

[Propofol: ED50 and ED90 induction doses in pediatric anesthesia].

OBJECTIVE: To study ED50 and ED90 induction doses of propofol in children. PATIENTS AND METHODS: Seventy-two children from 1 to 110 months of age and premedicated with pentobarbital 4 mg/kg participated in the study. Seven different doses of propofol (1.5, 2, 2.5, 3, 3.5, 4 and 4.5 mg/kg) were injected into the dorsal hand or foot vein in 30 seconds. We measured the response to application of the mask, corneal reflex and response to trapezius muscle compression 30 and 60 s after administration. A log-probit statistical analysis was used and complications were noted. RESULTS: The doses that produced 50% elimination of reflexes (ED50) or 90% elimination (ED90) in our patients were 1.74 and 3.95 mg/kg for response to mask; 2.47 and 4.26 mg/kg for elimination of corneal reflex; and 3.27 and 4.79 mg/kg for compression of trapezius. Frequency of pain upon injection was 74% and that of spontaneous movement was 12%. Apnea (breathing halted for longer than 20 s) occurred in 7% of our patients. We recorded no cases of broncho or laryngeal spasm, or skin rash. CONCLUSIONS: Induction with propofol is appropriate given the rarity of stimulant effects, but there is a high frequency of pain upon injection, limiting the usefulness of this drug for anesthetic induction in pediatrics. ED50 and ED90 varies depending on the stimulus assessed.

Age Factors↗
PubMedDate not supplied

Photorefractive keratectomy for myopia: 18-month results in 178 eyes.

To evaluate the predictability, efficacy, and stability of myopic photorefractive keratectomy (PRK), we present the results of 18 months of 178 consecutive myopic eyes. Results demonstrated a stable change in the power of the cornea with long-term corneal clarity.

Adult↗
PubMedDate not supplied

[Post-obstructive pulmonary edema after adenoid-amygdalectomy].

A two-years-old boy with Down's Syndrome and a small interauricular communication was given priority scheduling for adenoidectomy and tonsillectomy to correct subacute obstruction of the upper airway. The only noteworthy event during surgery was an SpO2 of 92% during mechanical ventilation with FiO2 of 0.5 from no apparent cause. The patient suffered acute respiratory insufficiency due to the post-obstructive pulmonary edema in the hours immediately following surgery. The incidence of post-obstructive pulmonary edema is higher than might be expected, as symptoms can be interpreted as aspiration pneumonitis or left ventricular failure. Given the high prevalence of adenoiditis and tonsillitis with varying degrees of airway obstruction in children, we consider it useful to report this case. Such patients should be monitored carefully in the early postoperative period.

Adenoidectomy↗