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Biomedical subjects

J Cophignon

Publications and source records attributed to J Cophignon.

At least 73 records · Page 4Linked to original sources

[Attempt at explaining decompensation of hydrocephalus by modifications of reticular activity].

A correlative study is done between observation of cases of shunted hydrocephalus with mesencephalic signs such as Parinaud's syndrome and a multiunitary recording of mesencephalic and bulbar reticular formation activities during acute and chronic intracranial hypertension in cats. Clinical and experimental data are first separately analysed and then superimposed. This results in analysing the evolution of such intracranial hypertension in three stages: first stage of "tolerance" with minimal clinical signs and no change of reticular activity; second stage of "uncompensation" when mesencephalic signs appear and with increased mesencephalic activity and unchanged bulbar activity; third stage of "exhaustion" where can be noted disorders of consciousness, decerebration fits, and cardiorespiratory disorders; mesencephalic activity falls down to lower levels than basal ones, bulbar activity increases first and then also decreases rapidly. This suggests a mechanism of exhausting stocks of monoamines but also of change of the local cerebral blood flow. Increase and then fall of the reticular activity may be the general way, even without any herniation, of evolution of any intracranial hypertension of traumatic or tumoral origin.

Cerebrospinal Fluid Shunts↗

[Total expansion of the orbit for micro-orbitism].

Micro-orbitism which follows the very early arrested development of the optic vesicles hinders the fitting of a prosthesis. A total enlargement of the orbit is proposed which restores the normal dimensions and enables facial symmetry to be re-established. The risks and advantages of this procedure are discussed.

Anophthalmos↗

Orbital expansion for anophthalmia and micro-orbitism.

In severe cases of microphthalmos or anophthalmos, the bony orbital cavity is often too small to allow one to create a satisfactory socket for a prosthesis. An omnidirectional expansion of the orbit, by osteotomies done in a step-like fashion, allows the creation of a larger bony cavity and improves the symmetry of the face. The risks of the craniotomy and of the mobilization of the free bone pieces are discussed.

Anophthalmos↗

[Dynamical study of cerebrospinal fluid at the spinal level during isotopic cisternography. 74 cases].

Physiology teaches that in addition ot be basic areas of C.S.F. resorption in the region of the cerebrum, supplementary zones exist situated in particular at the coverings of the spinal nerves. The aim of this study was a quantitative and dynamic analysis of spinal flow in 74 subjects, 64 of whom had clinical signs of communicating hydrocephalus. In certain of them, classical examinations provided no precise indications as to the appropriate neurosurgical procedure. Study of the dynamics and resorption of the C.S.F. in the spine would appear to provide new elements in assessment prior to the decision to insert a ventriculo-atrial valve.

Cerebral Hemorrhage↗

[Osseous angioma of the orbit].

The angiomas of orbital walls are very rare. The authors report a case of cavernous angioma growing into the external orbital wall in a young girl. The surgical excision of this angioma after embolization of the arterial supply of the tumor permits a plastic reconstruction of the orbital wall with good result.

Carotid Arteries↗

Subtotal reconstruction of the orbit after destruction by benign tumour.

We present five cases of reconstruction of the orbital walls after destruction by tumours. Treatment is based upon wide exposure through a bicoronal scalp incision and immediate reconstruction with autogenous iliac bone grafts. we do not recommend using foreign materials for reconstructing the orbit.

Adolescent↗