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Biomedical subjects

J Conway

Publications and source records attributed to J Conway.

222 records · Page 13Linked to original sources

The influence of tissue layering on microwave thermographic measurements.

Non-invasive thermal imaging and temperature measurement by microwave radiometry has been investigated for medical diagnostic applications and monitoring hyperthermia treatment of cancer, in the context of heterogeneous body structure. The temperature measured by a radiometer is a function of the emission and propagation of microwaves in tissue and the receiving characteristics of the radiometric probe. Propagation of microwaves in lossy media was analysed by a spectral diffraction approach. Extension of this technique via a cascade transmission line model provides an efficient algorithm for predicting the field patterns of aperture antennas contacting multi-layered tissue. A coherent radiative transfer analysis was used to relate the field pattern of a radiating antenna to its receiving characteristics when used as a radiometer probe, leading to a method for simulating radiometric data. Measurements and simulations were used to assess the effect of overlying fat layers upon radiometer response to temperature hot spots in muscle-type media. Results suggest that dielectric layering in tissue greatly influences measured temperatures and should be accounted for in the interpretation of radiometric data.

Fats↗

A robot-controlled microwave antenna system for uniform hyperthermia treatment of superficial tumours with arbitrary shape.

A system for microwave hyperthermia by scanning an antenna 'footprint' over a disease site is demonstrated. A computer-controlled robot arm scans a 2.45 GHz helical antenna and controls the absorbed power distribution. The 'ideal' power distribution required to achieve steady-state temperature uniformity over a given region has been calculated and a corresponding antenna trajectory programmed to approximate this pattern. Computer models, based on the solution of the bio-heat equation, have been implemented to allow various system parameters, such as antenna beam size, scan path and velocity profile, to be optimized. Experiments on a homogeneous muscle-equivalent phantom have shown that the scanning antenna system produces uniform temperature distributions over large areas of arbitrary shape. The addition of a thermal control system, based on temperature signal feedback, would enable 'real-time' modification of the power distribution and allow inhomogeneous and perfused tissue structures to be heated more uniformly.

Computer Simulation↗