Biomedical subjects
Publications and source records attributed to J Comas.
We present our 1-year experience in the management of esophageal foreign bodies in 31 adult patients, and we analyze the predisposing and risk factors, the diagnostic procedures, the removal techniques and the postoperative control and treatment.
Following a review of the world literature dealing with the incidence of remote metastases in tumours in the ENT field in general, and of the larynx and hypopharynx in particular, we present a study covering 927 patients suffering from cancer of the larynx and hypopharynx. The purpose of the research was to determine the incidence and position of metastases in this type of patient, and to determine their evolution. A total of 786 patients were followed over a minimum of 4 years, and 52 cases (6.7%) of metastases were recorded. They occur all the more frequently when the primary tumour is hypopharyngeal, of the low differentiated carcinoma type, or when there is a cervical ganglionic extension.
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The cavernous sinus is an unusual site for metastases from tumors of the larynx and pharynx. In postmortem studies of patients with cancers of the larynx, hypopharynx, and other sites, cavernous sinus metastases have been detected in very few cases. We present 3 cases of metastatic cavernous sinus disease. Despite the lack of pathologic diagnosis by biopsy, we feel that the clinical presentation combined with computed tomography provides an accurate diagnosis.
Spore suspensions of microsporidian parasites of fish (Microsporidium ovoideum, Glugea stephani, Glugea atherinae and Spraguea lophii) have been analyzed by flow cytometry. Spore nuclei were dyed either by propidium iodide or bis-benzimide (Hoechst 33342). By observation of forward light scatter and fluorescence the four species could be distinguished and the mono- and diplokaryotic populations of S. lophii identified. Staining of DNA by bis-benzimide was better and easier than propidium iodide. Forward light scatter and fluorescence values were characteristic of each species and remained unchanged throughout the year, so flow cytometry can be used for distinction of spores of some microsporidian parasites once their flow cytometric parameters are known. However, special care has to be taken in tool calibration and material preparation for analysis because of the high precision of the technique.