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Biomedical subjects

J Colville

Publications and source records attributed to J Colville.

At least 19 recordsLinked to original sources
PubMed1991

Person-to-person transmission of Brucella melitensis.

Human brucellosis is primarily an occupational hazard in the USA; in the Middle East and Africa ingestion of contaminated dairy products is an important route of infection. Whether human beings can become infected via person-to-person spread is uncertain. During an investigation of a commonsource, laboratory-associated outbreak due to Brucella melitensis, biotype 3, the wife of a microbiologist with serologically proven brucellosis became infected. Her blood isolate was indistinguishable from the epidemic strain. In the absence of other risk factors, we suggest that sexual intercourse is a possible means of transmission.

Brucella↗
PubMed1991

Outbreak of Brucella melitensis among microbiology laboratory workers in a community hospital.

From May to September 1988, eight employees of a microbiology laboratory developed acute brucellosis (attack rate, 31%). Seven of the eight affected employees had clinical illness ranging from a nonspecific, flulike illness to severe hepatitis. Blood cultures obtained from five of the affected employees (63%) were positive for Brucella melitensis, biotype 3. Comparison of cases and controls showed that there were no risk factors besides employment in the laboratory. Based on work locations, assignments, and interviews, it was found that person-to-person, droplet, food-borne, and waterborne spread were unlikely. Our investigation disclosed that 6 weeks before the outbreak began, a frozen brucella isolate from a patient hospitalized 3 years earlier had been thawed and subcultured without the use of a biologic safety cabinet. This clinical isolate was subsequently identified as B. melitensis, biotype 3, identical to the employee isolates. It is presumed that transmission occurred via the airborne route. This outbreak reemphasized that all work on Brucella species, an established biosafety level 3 organism, must be conducted under a biologic safety hood. Furthermore, it might be prudent to perform all clinical "setups" under a safety hood since aerosolization commonly occurs during the initial processing of specimens and the majority of these specimens are from patients with uncertain diagnoses.

Brucellosis↗
PubMed1990

Spontaneous rupture of the biceps femoris.

A case is reported of spontaneous rupture of the biceps femoris muscle, a hitherto undescribed condition. A characteristic history is discussed and a new clinical sign described.

Adult↗
PubMed1989

Early active mobilisation following flexor tendon repair in zone 2.

In a prospective study, 114 patients with 138 zone 2 flexor tendon injuries were treated over a three-year period. Early active mobilisation of the injured fingers was commenced within 48 hours of surgery. 98 patients (86%) were reviewed at least six months after operation. Using the grading system recommended by the American Society for Surgery of the Hand, the active range of motion recovered was graded excellent or good in 77% of digits, fair in 14% and poor in 9%. Dehisence of the repair occurred in 11 digits (9.4%) and in these an immediate re-repair followed by a similar programme of early active mobilisation resulted in an excellent or good outcome in seven digits.

Adolescent↗
PubMed1989

Syndactyly correction.

The operation to be described has been used by the author, with minor modifications, for over 10 years. A series of 57 cases is presented, all of which were simple, uncomplicated examples of syndactyly. The correction is based on separation of the cleft into rectangular flaps combined with removal of interdigital fat. Performed at one year, this allows complete closure of the ulnar side of the cleft and, in mild degrees, complete closure of the radial side also. A dorsal island flap is used to reconstruct the web. The results have been assessed with a minimum follow-up of 2 years and are discussed.

Female↗
PubMed1986

Familial congenital muscular torticollis: case report and review of the literature.

A family history of congenital muscular torticollis is uncommon. Only a small number of cases have been reported in the English literature. This is a report of five female children who are interrelated and have congenital muscular torticollis. Three of the children are sisters, and four are the offspring of consanguineous matings. No environmental factor could be identified that would predispose the children to congenital muscular torticollis. In this family, it is apparent that genetic factors are influencing the development of this condition. The cause of congenital muscular torticollis is unknown, but heredity may play a more important role than has previously been suspected.

Child↗
PubMed1984

Excision arthroplasty for infected total hip replacements.

A study of excision arthroplasty (Girdlestone's pseudarthrosis) for infected total hip replacements is presented. Twenty-two patients were reviewed with a minimum follow-up of one year. Reduction in pain was significant but the functional results were poor. Factors contributing to poor function were old age, poor medical condition and arthritis of the contralateral hip; these were in addition to the gross instability resulting from the pseudarthrosis. The patients were easily fatigued and dependent on external supports; calipers were found to be unacceptable. The symptoms after excision arthroplasty are compared with those before the original hip replacement.

Aged↗
PubMed1983

Dupuytren's contracture--the role of fasciotomy.

This paper summarises the results obtained in 95 patients treated by fasciotomy, defines the indications for this procedure and describes the operative technique. During a period of seven years a total of 95 patients with 137 fingers affected by Dupuytren's Contracture have been treated by fasciotomy. The minimum follow-up is two years. The oldest patient was 79 years and no patient younger that 50 years was accepted for this form of treatment.

Aged↗