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Biomedical subjects

J Collins

Publications and source records attributed to J Collins.

At least 433 records · Page 24Linked to original sources

The post-suicide family and the family physician.

It is estimated that there are 750,000 people each year who are intimately affected by suicide. Prominent among these are the family survivors and their family physician. This paper offers a time frame which divides the period following the suicide into three phases: Immediate (the first ten days after the suicide); Intermediate (after the first ten days through the first year); and Extended (from the first year until restitution occurs). It identifies the chief emotional reactions which occur in each phase, explores their psychodynamic origins, and proposes suggestions for appropriate management during each of the three periods. The goal of this plan of management is to enable the family physician to function in a supportive emphatic, and restorative manner for the post-suicide family.

Depression↗

Plasmid ColE1 DNA replication in Escherichia coli strains temperature-sensitive for DNA replication.

Mutants of the dnaA, dnaC, dnaD, polC, dnaF and dnaG gene loci were tested for their capacity for colicinogenic plasmid E1 (ColE1) replication at a non-permissive temperature. It was found that ColE1 replication was independent of the dnaA gene function and dependent on dnaC, D, F and G. ColE1 replication in the polC mutant E486 continued for several hours but at a greatly reduced rate. No effect was found of the dnaG mutation on thymine-deprivation-induced "priming" of ColE1 replication at the non-permissive temperature. The mutants also were tested for aberrant replication intermediates of plasmid DNA as well as a temperature sensitive supercoiled DNA-protein relaxation complex. RNA-containing supercoils were found to accumulate in a poIC mutant also blocked for protein synthesis.

DNA Replication↗

Independence of F replication and chromosome replication in Escherichia coli.

Data are presented which show that F replication is not coupled to any stage of the replication cycle of the host chromosome or to cell division, and is probably not related to surface area. It is also shown that the initiation mass of F increases progressively as the growth rate increases, the number of copies of F per unit of mass falling by half between doubling times of 0.8 and 2.7 generations per hour. It is further shown that the presence of an F particle does not influence the initiation mass of the chromosome.

Chromosomes, Bacterial↗

Presence of a dialysable fraction in normal bovine whey capable of killing several species of bovine mycoplasmas.

Most normal bovine whey samples contain a fraction that survives heating at 56 degrees C. for 30 min., passes through a dialysis membrane and kills a maximum of seven out of ten of the different bovine mycoplasma species tested. Some whey samples appear more active than other but not all affect the same strains of mycoplasma indicating some specificity in their action. Absorption of the active factor from whey by heterologous and homologous mycoplasmas and by erythrocytes was observed. Binding of the factor to mycoplasmas appears to be temperature-dependent and non-specific, but subsequent mycoplasmacidal action shows some specificity.

Absorption↗

Analysis of traditional strategies to combat world hunger and their results.

The traditional strategies proposed for development of the agricultural production of the underdeveloped countries are examined in this article. It is shown that the application of these strategies in the past has proven insufficient to eliminate world hunger. The limitations of these strategies are discussed and proposals are made for achieving the agricultural development in the underdeveloped world that will be necessary to eliminate hunger in the near future.

Agriculture↗

Assessment of the world food situation-present and future.

The widespread bad harvests of 1972 in various regions of the world, the consequent reduction in grain reserves, the rapid rise in food prices almost everywhere and its impact on inflation, all have served to draw renewed attention to the problem of hunger which affects millions of human beings in the world today. During the 1974 United Nations World Food Conference many important matters relating to this problem were debated: the creation of international grain reserves; problems concerning world trade of foodstuffs; the current difficulties with certain key agricultural production factors, such as fertilizers; the necessity for organizing a worldwide information system on the situation; and prospects of various harvests and threats of famine in underdeveloped countries. It is often the case that discussion of the hunger problem does not correspond to the gravity of the crisis; true causes of the present situation are not examined, and measures are not adopted that will once and for all--for the first time--abolish hunger. In view of the prospect that the real issues are often ignored, the Transnational Institute provides this analysis in an attempt to clarify what must be done to abolish hunger in the belief that this is within the reach of humanity when and if we are determined to end the irrationalities of the present economic system and the relations of domination which some individuals and countries seek to continue.

Agriculture↗

Serological comparison and haemagglutinating activity of Mycoplasma dispar.

A comparison of twelve strains of Mycoplasma dispar by the metabolism inhibition and indirect haemagglutination tests has shown them to form a serologically homogeneous group of micro-organisms. The twelve strains vary in their haemagglutinating activity against erythrocytes from different animal species, and certain of the strains can be distinguished by the erythrocytes they agglutinate. Haemagglutination may thus provide a method by which certain strains can be typed. The erythrocyte receptor site does not appear to contain sialic acid and is not sensitive to proteolytic enzymes. On the mycoplasma cell two attachment sites have been demonstrated. One, by which it attaches to sheep and bovine erythrocytes, is a protein or contains a protein moiety. The chemical nature of the other attachment site, by which M. dispar attaches to rabbit erythrocytes, is unknown.

Animals↗