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Biomedical subjects

J Col

Publications and source records attributed to J Col.

29 records · Page 2Linked to original sources
PubMed1985

Acute haemodynamic effects of ibopamine in patients with severe congestive heart failure.

Ten patients with congestive heart failure (CHF), in III and IV NYHA Class, were treated orally with a single dose of ibopamine ranging from 1.2-3.3 mg/kg, and were studied using the Swan-Ganz catheter and thermodilution technique. Cardiac index (CI) and stroke volume index (SVI) were increased, and mean pulmonary pressure (PAP), systemic vascular resistances (SVR) were lowered. Ibopamine increased CI (+33%) and SVI (+26%), and decreased PAP (-17%) and SVR (-24%). All changes were statistically significant. The maximum haemodynamic effect occurred 180 min after ibopamine administration. Blood pressure and heart rate were unaffected. Tolerability was good. This study shows that ibopamine when orally administered to human subjects improves cardiac performance and further investigations on its use as a therapeutic agent in the long term treatment of CHF are recommended.

Adult↗
PubMedDate not supplied

Orthotopic heart transplantation eleven years after left pneumonectomy.

Orthotopic heart transplantation was performed in a 21-year-old medical student 11 years after left pneumonectomy for a rhabdomyosarcoma. The cardiomyopathy was the result of the administration of doxorubicin (Adriamycin). The surgical procedure was largely facilitated as a result of an in-hospital donor and the absence of major adhesions. The early postoperative course was mainly uneventful. The patient is doing well 9 months after operation, without any episode of rejection or infection.

Adult↗
PubMedDate not supplied

[Hemodynamics and massive pulmonary embolism].

In massive pulmonary embolism, the hemodynamic evaluation means a Swan-Ganz catheter and echocardiography, may be indicated as a hemodynamic assessment in correlation to the degree of obstruction and as a therapeutic guideline. Some figures demonstrate the importance of some hemodynamic parameters in order to choice the adequate therapy. Inconvenience and precautions of the method are shortly mentioned.

Bronchi↗