Whole allergenic extracts (WAE) from plane-tree pollen induces in vitro blastogenesis in splenic lymphocytes from primed and normal rats. Allergen P, the major allergen of plane-tree pollen, induces an early stimulation in primed cells. WAE induced in the same way an early stimulation in primed cells, but a late incorporation of 3H-thymidine occurs at 8 days of culture when lymphocytes from primed or normal rats were used. This late response appears to be non-specific and is not abolished when a short-pulse of antigen is given.

Allergens↗

PubMedDate not supplied

[Diagnosis of prolonged eosinophilic pneumopathies].

Prolonged pulmonary eosinophilia are defined by the association of a pneumonia and a blood eosinophilia persisting for over a month. They cover a wide range of disorders : prolonged Loeffler's syndrome, Carrington's chronic eosinophilia pneumonia, allergic bronchopulmonary aspergillosis, necrotizing vasculitis as Churg and Strauss allergic granulomatosis and angeitis and polyarteritis nodosa, and the hypereosinophilic syndrome. All these conditions may form a continuum centered by the poorly defined chronic eosinophilic pneumonia. This entity may result from a non treated Loeffler's syndrome or may progress to the severe necrotizing vasculitis or hypereosinophilic syndrome.

Adult↗

PubMedDate not supplied

Bronchial hyperreactivity.

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Asthma↗

PubMedDate not supplied

[Asthma and environment (author's transl)].

Asthma which includes an important bronchial hyper-reactivity to several substances is closely linked to environmental factors. Atmospheric allergens are among the best known of these factors. Some and the most numerous, like pollen, are natural. Others like isocyanates are artificial and mostly the cause of professional accidents. The noxious effect of air pollution on airways has been clearly established by the numerous observations compiled over half a century. As far as asthma is concerned, the bronchoconstricting effect of pollutants inhaled at high doses is well known. Numerous epidemiological studies and tests performed in laboratories have also revealed the action of different pollutants inhaled at "realistic" concentrations. The relationship between asthma and climatic environment appears more difficult to define and the objective facts which could play a part in these relations are few and contradictory.

Adult↗

PubMedDate not supplied

[Bronchial response to allergens after controlled NO2 exposure (author's transl)].

The bronchial response to inhaled grass pollen (assessed by specific airway resistance, SRaw, measurements) was determined in seven allergic patients after each had spent 1 hour in an exposure chamber breathing on one occasion unpolluted air and on a separate occasion (one week interval) a mixture of air and nitrogen dioxide (NO2, 207 micrograms/m3). Sequences of exposure to unpolluted air and to NO2 were randomized in a single-blind fashion. No significant change in baseline SRaw or in the response to antigen was observed after NO2 exposure.

Adult↗

PubMedDate not supplied

[Dermatology].

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Allergy and Immunology↗

PubMedDate not supplied

[Frequency of chronic rhinitis in a population of young adults. Influence of pollen allergy and tobacco addiction (author's transl)].

A survey of 27 604 sujets aged mostly between 17 and 19 revealed that 33.5% of them had a regular nasal obstruction and that 13.6% repeated sneezing fits. Prevalence of nasal manifestations related to an allergy to graminaceae pollen was estimated at 5%. Besides there was a close relationship between the chronic nasal symptomatology and the smoking habits of the subjects concerned.

Adolescent↗

PubMedDate not supplied

[Spirometric measurement of airway response to carbachol in asthma (author's transl)].

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Adolescent↗