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Biomedical subjects

J Charnley

Publications and source records attributed to J Charnley.

At least 73 records · Page 4Linked to original sources

Prediction of thromboembolism following total hip replacement.

Obesity, edema in the legs before surgery, a history of deep venous thrombosis, varicose veins, and a diagnosis of osteoarthrosis were associated with an increased risk for postoperative thromboembolism. Selective administration of anticoagulants to high risk but not to low risk patients should result in a reduction in total mortality following surgery. It is therefore suggested that when deciding whether prophylactic anticoagulants should be administered to a patient, consideration should be given to that patient's likelihood of developing fatal pulmonary embolism if the anticoagulant is not given, compared to the potential reduction in his risk for fatal pulmonary embolism and the increase in risk for fatal bleeding complications if the anticoagulant is used.

Adult↗

Changes in the upper femur after low friction arthroplasty.

In 169 low friction arthroplasties, an extension to 10 years of the radiological appearances, noted at 4 years after acrylic cement had been in the medullary cavity of the femur, there was no grossly visible evidence of deterioration. An increased number of femora showed hypertrophy with normal bone texture. The number showing atrophy remained the same at about 4.8%. Absorption of the medial neck of the femur averaged 5.5 mm over the whole study and was often preceded by small cystic areas. Evidence of demarcation of cement from the endosteal surface of the femur was absent in 66%. When demarcation did occur, in most cases it was confined to the tip or below the midlevel of the stem. In only 2.4% did it reach slightly above the midlevel. No tendency could be found for the radiological appearances of medial femoral neck absorption or cement demarcation to predominate in patients with lower grade levels of function. Improved techniques, by which more perfect fixation between cement and bone in the upper level of the prosthetic stem is achieved, may eliminate instances of loosening and localized bone erosion encountered elsewhere.

Absorption↗

Eight year results of Charnley arthroplasties of the hip with special reference to the behavior of cement.

Five hundred and forty-seven total hip replacements by the Charnley technique during 1967 and 1968 have been studied for the quality of the late results. The average follow-up was 8.3 years. Mechanical failure at the cement-bone interface occurred in only 2.2% of cases. A search was specially directed towards evidence of incipient pathology at the bone-cement interface in the absence of any suspicion of clinical defect. This was found in 12% of cases but it is emphasized that the criteria were exceptionally rigorous and entirely radiological. Because the cement technology used at that time is now considered unsophisticated, mechanical failure of cement is a preventable condition. A previous report of socket migration in 9.5% of cases is not confirmed by the present survey of a more recent series of cases.

Adult↗

Socket wear in Charnley low friction arthroplasty of the hip.

Five hundred forty-seven Charnley hip arthroplasties were measured for wear radiographically after an average period of 8.3 years. The operations were performed in 1967 and 1968 and the average rate of wear was 0.07 mm per year. This is only half that recorded for the operations in 1963, 1964, and 1965. Clinical radiographic methods of measuring socket wear are valid provided that the socket is inserted with the wear marker not more than 10 degrees from the coronal plane. This can be estimated provided that radiopaque cement is used.

Adult↗