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Biomedical subjects

J Cerný

Publications and source records attributed to J Cerný.

At least 109 records · Page 6Linked to original sources
PubMed1988

Serum aldosterone studies in 10 calves living for 2-5 months with a total artificial heart (TAH).

A group of 10 experimental calves that lived for 61-147 days with a TAH was used to study serum aldosterone levels by RIA with ALDOCTK-125 CEA Kit (Sorin Biomedica, Italy). The aldosterone levels were plotted against the serum sodium and potassium, body weight, CVP, urinary sodium and potassium and with hematocrit levels. In these experiments, three types of TAH (TNS-BRNO II, VII, and Rostock) were used. The levels of aldosterone were already high before the surgery and during the entire pumping period, which indicates the development of secondary aldosteronism. The study deals with the mechanisms that participate in the development of aldosteronism in each phase of the experiment with the TAH.

Aldosterone↗
PubMed1987

[Local blood flow in the gastric wall after proximal selective vagotomy in rats].

The influence of the proximal selective vagotomy (PSV) on the local blood flow in the gastric wall was investigated. No significant changes of the microcirculation were established in the mucosa of the corpus ventriculi (secretory area). The blood flow in the antrum pylorus was increased temporarily 24 hours after PSV and it was normalized again 4 and 7 days later. Pentagastrin led to a significant increase of the blood flow in the gastric wall of a control group and also in the operative group 24 hours after PSV. Pentagastrin was without any influence on the microcirculation after PSV are no cause for ulcer relapses.

Animals↗
PubMed1986

Control and driving of pneumatic total artificial hearts TNS-BRNO-II and -III in long-term experiments.

Hemodynamic analysis was carried out during long-term experiments with the pneumatic total artificial hearts TNS-BRNO-II and TNS-BRNO-III to determine standard methods of starting artificial hearts and criteria for their long-term operation in vivo. In long-term experiments, regulatory mechanisms automatically regulating the systole length and diastolic aspiration pressure have also been verified. Comparison of hemodynamic variables obtained from invasive measurements with pneumatic pressure curves permitted the control and monitoring of the experiment in its entirety by noninvasive methods only. The control of the artificial heart using the Chirasist TN 3 and Chirasist TN 4 was adapted to specific properties of the pumps, above all to the functions of the atypical inlet valves. The terminal stages of the experiments have shown that a 100-ml pump can ensure survival of experimental calves up to 210 kg body weight.

Animals↗