Search PubMed⌕ Search

Biomedical subjects

J Cayla

Publications and source records attributed to J Cayla.

At least 37 records · Page 2Linked to original sources
PubMed1982

[Hemarthrosis of articular chondrocalcinosis. Apropos of 28 cases. Importance of treatment by isotopic synoviorthesis].

32 cases of hemarthrosis observed in 26 patients suffering from articular chondrocalcinosis are used as a basis for a review of the principal clinical anc paraclinical findings. Special mention is made of the fact that hemarthrosis occurs in the shoulder much less rarely than has been classically reported. The diagnostic value of finding microcristals of calcium pyrophosphate in hemorrhagic fluid is also emphasized. In addition to standard treatment, isotopic synoviortheses is shown to be effective for treatment of recurrent hemarthrosis. After an average of 3.3 years of follow-up, this treatment, although lacking certain analgesic effect, frequently leads to lasting cessation of the hemarthrosis, more often it seems, in the shoulder than in the knee.

Aged↗
PubMed1979

[Medullary compression revealing the presence of an epidural nodular lymphoma (author's transl)].

A case of medullary compression is reported which was found to be due to an epidural lymphoma of the nodular type, which was centrofollicular, with only slight lymphocytic differentiation, and appeared to be isolated. The hour-glass appearance of the tumour suggested, however, that it was not the primary tumour. The short term outcome appeared to be favourable after surgery and radiotherapy but a limited period of chemotherapy is being given. Reports on the frequency of medullary compression during malignant non-Hodgkinson lymphomas vary between 1 and 15% of cases, and many cases have revealed the actual cause, especially in neurosurgical practice. Most authors do not accept the existence of lymphomas primarily located in the epidural space, and feel that they result from metastatic invasion or by contiguity. Prolonged survival can be hoped for after mixed treatment of these tumours, especially in histologically favourable forms.

Aged↗
PubMed1978

[Controlled trial of levamisole in rheumatoid arthritis. Clinical and immunological study of 22 cases (author's transl)].

The results of a controlled trial in 22 patients indicated that levamisole, administered in a dose of 150 mg per day for 2 months, was more effective than a placebo on the clinical symptoms and signs of rheumatoid arthritis. Side effects were seen in 8 of the 12 patients treated with levamisole. They necessitated the premature interruption of treatment in three, but were never serious (no cases of agranulocytosis were seen). In the group treated with levamisole, there was a slight decrease in sedimentation rate, a significant fall in levels of the C3 fraction of serum complement and of circulating immune complexes (detected by polyethylene glycol), and a significant increase in cutaneous reaction to tuberculin and to candidin. By contrast, there were no significant variations in levels of rheumatoid factor, serum immunoglobulins, C4 fraction of complement, lymphocyte transformation indices in the presence of six dilutions of phytohaemagglutinin, nor in the percentages of T and B lymphocytes. The effectiveness of levamisole in rheumatoid arthritis would appear to be demonstrated, but its mode of action remains open to discussion, in the absence of any definite correlation between therapeutic activity and the immunostimulant effects of the drug.

Antigen-Antibody Complex↗
PubMed1978

[Reflex algodystrophy of the lower limbs during pregnancy].

Four cases of neurotrophic rheumatism during the course of pregnancy are reported. Observations in 9 cases from the literature allowed the isolation of the principal features of this sort of algodystrophy. It occurs in the last trimester of pregnancy, attacking usually and almost exclusively the lower limbs, especially the left hip. There is rapid resolution after delivery, occasionally preceded by a rebound in the post-partum period. Responsability of pregnancy as the cause of the neurotrophic rheumatism is not in much doubt. It apparently arises from a shift of mechanical factors linked with the uterine enlargement which without doubt causes pressure of the pelvic sympathetics.

Adult↗
PubMed1977

Gout and hyperlipidaemia. Effect of overweight on the levels of circulating lipids.

A study of the serum lipids in 90 patients with gout and 90 controls matched for age and weight index demonstrated that in gout there was a significant elevation of the mean serum levels of cholesterol (282 +/- 55 mg/100 ml), triglycerides (183 +/- 161 mg/100 ml) and phospholipids (270 +/- 61 mg/100 ml) compared with the controls whose mean values were respectively 243 +/- 41 mg, 95 +/- 53 mg and 245 +/- 36 mg. Hyperlipidaemia of mixed type was the most common lipid defect in the patients with gout; there was no difference in the frequency of pure hypercholesterolaemia (without hypertriglyceridaemia) between gout and the controls. The frequency of anomalies of blood lipid levels in gout does not result from (or not solely from) obesity since patients with gout and controls were matched for their weight and height. There was a correlation between the serum lipid levels and obesity in the controls but this was not demonstrable in the patients with gout.

Adult↗
PubMed1976

A controlled trial of ketoprofen (administered rectally) in arthritis of the hip and knee.

A double-blind therapeutic trial carried out by the sequential method has demonstrated clearly a significant difference in efficacy between ketoprofen (given rectally at a dosage of 200 mg daily) and a placebo in a group of patients suffering from osteoarthritis of the hip or knee. The interest in this type of study lies in the fact that it will often given the answer to a simple question using a relatively small number of patients.

Aged↗