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Biomedical subjects

J Castillo

Publications and source records attributed to J Castillo.

At least 217 records · Page 12Linked to original sources

[Campylobacter enteritis].

Authors report results of the study of a series of 50 children patients with Campylobacter enteritis. After insisting on the present frequency of this infectious agent as pathogen for human beings, they analyse the epidemiologic, clinic and therapeutic aspects.

Anti-Bacterial Agents↗

[Aicardi syndrome].

The association in young girls of flexion spasms of early beginning, partial or total agenesis of the corpus callosum, severe chororetinopathy and frequent skeletal anomalies is known as the Aicardi syndrome. On occasion of two observations a review of the literature is made.

Abnormalities, Multiple↗

[Computerized cerebral tomography in tuberous sclerosis. Study of 3 patients].

The findings on computerized axial tomography of the brain in three patients with tuberous sclerosis are reported. Numerous intracranial calcified nodules varying in size from a few millimeters to one centimeter, located preferentially below the ependyma of the lateral ventricles and determining filling defects in its lumen were found in all cases. Other calcified lesions were found in a subcortical location. One patient presented areas of low density throughout the hemispheric white matter, and another showed ventricular dilatation of the ventricles and basal cisternas. Computerized axial tomography is useful in the evaluation of patients with tuberous sclerosis because of its early demonstration of the characteristic intracranial lesions and detection of complications such as calcification of basal and cerebellar ganglia, hydrocephalus, and development of gliomas. Low density areas may correspond to foci of demyelinization. Furthermore, computerized axial tomography allows the demonstration of cerebral tuberosities in asymptomatic relatives, thus offsetting the inconveniences of pneumoencephalography.

Adult↗

[Cytomorphological study of the cerebrospinal fluid. II. Leukemias and lymphomas (author's transl)].

A cytological study of the cerebrospinal fluid from 25 patients with acute leukemias and five patients with malignant lymphomas (Hodgkin's disease and non-Hodgkin's lymphoma) has been performed. All patients had clinical manifestations of central nervous system involvement at the time of lumbar puncture. Cytological abnormalities were observed in 13 out of the 30 samples examined (positivity: 44 percent). The group of 17 patients with lymphoblastic leukemia accounted for the highest cytological positivity (12 our of 17 cases --70.5 percent--). Cerebrospinal fluid from eight patients with acute myeloblastic leukemia and from four patients with Hodgkin's disease was normal. Numerous cell atypias were found in a case of lymphocytic lymphoma. The importance of systematic cytological study of the cerebrospinal fluid in patients with leukemia in order to prevent recurrences and to control intrathecal administration of cytostatics and/or radiotherapy is stressed.

Cerebrospinal Fluid↗

[Behçet's disease: report of ten cases and of a new clinical manifestation (portal vein thrombosis) (author's transl)].

Ten patients (seven males and three females) with the diagnostic criteria for Behçet's disease are reported. Symptoms began between ages 14 and 37 (mean age 27.9 years), and the time of evolution of the disease varied between one and 23 years (mean 5.7 years). Initial presentation was aphthous stomatitis (three cases), ocular inflammation (three cases), erythema nodosum (one case), arthritis (one case), thrombophlebitis (one case), and hemorrhagic proctocolitis (one case). During the course of the disease the commonest clinical manifestations were oral and genital ulcerations (100%) and ocular (70%), cutaneous (70%), articular (40%), neurological (40%), venous (40%), gastrointestinal (40%) and arterial (10%) involvement. Increased erythrocyte sedimentation rate was a constant feature in all patients. HLA-B5 antigen was determined in four patients, being positive in two of them. Cerebrospinal fluid alterations were present in the four patients with neurological involvement even though three of them never had meningeal symptoms. One patient developed portal hypertension secondary to portal vein thrombosis, and its clinical manifestations are described.

Adolescent↗

[Cytomorphology of the cerebrospinal fluid. I. Tumors of the central nervous system (author's transl)].

A cytomorphological study of the cerebrospinal fluid corresponding to 42 patients with tumors of the central nervous system has been performed. The group of 31 patients with primary tumors accounted for an overall cytological positivity of 32.2 percent; according to the type of tumor cytological positivities were as follows: glioblastoma multiforme (44.4 percent); grade I/III astrocytoma (33.3 percent); oligodendroglioma (33.3 percent); ependymoma (25 percent), and meningioma (16.6 percent). In the group of 11 patients with metastatic tumors, neoplastic cells were observed in two cases (cytological positivity 18.1 percent). Cytological study of the cerebrospinal fluid is a useful diagnostic method for some primary and secondary neoplasms of the central nervous system.

Brain Neoplasms↗