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Biomedical subjects

J Castella

Publications and source records attributed to J Castella.

31 records · Page 2Linked to original sources

Lung cancer in patients with tracheostomy due to cancer of the larynx.

During 3 years, a prospective study was undertaken to investigate the frequency of lung cancer (LC) in patients with a tracheostomy after laryngectomy for neoplasm of the larynx (LxC). The protocol required a thorax radiography (RX) and a bronchofiberscopy (BF) every 6 months in each patient. Of the 286 cases studied, a diagnosis of LC was made in 36 (12.5%). In 6 of these 36 patients, there were no symptoms suggestive of LC and the RX was normal, and the diagnosis of LC was made only by systematic BF. A surgical treatment of LC was possible in only 7 cases. These results suggest that there is a high frequency of LC in patients with tracheostomy due to LxC, and also that it would be better to restrict the follow-up with systematic BF to those patients suitable for thoracotomy.

Aged↗

Cytology of postbronchoscopically collected sputum samples and its diagnostic value.

The usefulness of the cytology of postbronchoscopically collected sputum (PBS) samples in the diagnosis of neoplastic lung disease has been studied in 113 cases. The overall diagnostic yield of fiberoptic bronchoscopy (FB) alone was 77%, 87% in 77 central tumors and 58% in 36 peripheral ones. With the addition of PBS, the positive results increased to 91% in the 113 cases (p less than 0.01), to 94% n central tumors (p greater than 0.05) and to 83% in peripheral lesions (p less than 0.02). In 15 cases PBS offered the unique positive results. 73 cases with histological confirmation showed a good cytohistological correlation in 82%. Our report suggests that PBS is a useful technique in the diagnosis of lung cancer. Its systematic use does not seem to be justified in central tumors, but it is of great value in peripheral tumors when fluoroscopic control is not available.

Adult↗

Tracheobronchopathia osteochondroplastica.

6 cases of tracheobronchopathia osteochondroplastica are discussed. Diagnoses were established ante mortem. Endoscopic examination was performed in 3 patients because of hematic expectoration, in the other 3 cases the induction was given by chronic bronchorhea, slow-resolving pneumonia and suspected neoplasia, respectively. Calcification and cartilaginous areas were restricted to a small portion of the tracheobronchial tree in 1 of the cases; in 3 cases the disease affected the trachea and both main bronchi, whereas it was found markedly spread throughout the trachea in the last 2 patients. Tracheal tomography and bronchoscopic examination are considered the methods of choice for an ante mortem diagnosis of this disease.

Adult↗

Nomenclature proposal for postsegmental bronchi.

The use of flexible fiberoptic bronchoscopy has given a chance to deeper visualization of the bronchial tree. For this reason, the classical bronchial nomenclature becomes much more annoying when denominating pathological processes located in the most peripheral bronchi. The authors suggest a new nomenclature for an easier and more practical use.

Bronchi↗