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Biomedical subjects

J Carrillo

Publications and source records attributed to J Carrillo.

32 records · Page 2Linked to original sources
PubMed1982

[Antigenic cross-reaction between neonatal intestinal mucosa and certain serotypes of Escherichia coli].

In the soluble and insoluble fractions of three intestinal mucosa of neonates, a study was made of the contents of Kunin's (ECA) common heterogenous antigen, and of somatic antigens of different E. coli serotypes. In the three mucosas, evidence was found that a fraction capable of hindering the antiserum anti-014, (antiserum anti-ECA), does exist. It was also discovered that the three mucosas have a variable content of substances which hinder antiserums contrary to different somatic antigens of various E coli's serotypes. Furthermore, the soluble and insoluble fractions of the intestinal mucosas "combine' when they are preincubated with some of the crude lipopolysaccharides (LPS) of E. coli enteropathogens and non-enteropathogenes, according to the determining antigens be they divided into equal parts or not. This last phenomenon modifies, in variable degrees, the capacity of these fractions to hinder the antiserums contrary to the determinative equal parts with E. coli. Based on the above observations, the author proposes a hypothesis in order to explain the different behaviour, (pathogen and/or commensal), of a similar E. coli's serotype when it settles in the intestine of different people

Antigens, Bacterial↗
PubMedDate not supplied

Enterobacterial common antigen in the urine from children with cancer.

An inhibition of immunohemolysis assay was used to detect the enterobacterial common antigen (ECA) in urine samples from 40 children with cancer. Seven patients were excluded because bacterial contamination of urine. Thirty of the remaining 33 sterile samples gave an ECA-positive reaction. Specimens from 30 healthy control were negative. These findings may reflect a vascular dissemination and glomerular filtration of gram-negative lipopolysaccharide residues as a consequence of the malignancy. Detection of ECA in urine may be an useful tool for investigating the evolution of neoplastic diseases in the absence of urinary tract infections.

Antigens, Bacterial↗
PubMedDate not supplied

[Protein electrophoresis and immunoglobulin concentration in the serum of children with amebic liver abscess].

The concentration of immunoglobulins G and M plus the electrophoretic profile of proteins was studied in the serum of 14 children with amebic liver abscess. There were different degrees of weight loss and of liver necrosis in all of them. The concentration of total proteins of the serum was subjected to different factors and resulted with wide individual variations. The same was obtained when the values of the fractions separated by electrophoresis were expressed in g/dl. On the other hand, percentual values gave a similar profile for all of the patients. Besides the significant increases of IgG. an inversion of the albumin/globulins ratio was found and an increase of the percentages of alpha-1, alpha-2 and gamma fractions. The importance that proteolytic anti-enzyme mechanisms may bear in the evolution of the lesion brought about in the liver by the enzymes liberated by the protozoa, is speculated.

Blood Protein Electrophoresis↗
PubMedDate not supplied

[Results of combined therapy in rhabdomyosarcoma in children].

In a study of rhabdomyosarcoma in children, 16 cases were treated and followed since 1971. Eight patients were staged I and II A and presented a mean survival time of 52 and 21 months respectively, whereas the remaining 8 patients were staged II B and III with a mean survival time of 20 and 9 months respectively. Of the 16 patients treated, 10 (62.5%) continue survival with an overall median survival time of 25 months. It is suggested that an early diagnosis and combined treatment including surgery, radiotherapy and chemotherapy with vincristine, cyclophosphamide and actinomicin and possibly adriamycin as a fourth drug, will give patients in underdeveloped countries, similar survivals and relief as those observed in developed countries. It is apparent that a multidisciplinary medical team is more important than the magnitud of economical resources.

Antineoplastic Agents↗
PubMedDate not supplied

[Treatment of acute myocardial infarction with rt-PA in 60 minutes. Cooperative study].

UNLABELLED: Thrombolytic therapy (TT) modifies the natural history of acute myocardial infarction (AMI) diminishing morbi-mortality rate. In recent studies, modification of infusion velocity, decreased the mortality 10 percentage points. OBJECTIVE: Test if rt PA administration over an hour is safe and practical. MATERIAL AND METHODS: A prospective, cooperative trial during 3 years, included patients with AMI with less than 6 hours of the onset of symptoms that received rt-PA therapy. Initially 10 mg bolus and then 90 mg over 60 minutes period. Together with the administration of rt-PA, 5000 units of heparin was given, followed by 1000 units per hour adjusted to keep PTT at 1.5 to 2 times normal. All patients received aspirin and according of the evolution adjuvant therapy. We defined bleeding complications and/or cerebrovascular accident related to thrombolytic therapy. RESULTS: We included 225 patients who received rt-PA. Average age was 57.1 +/- 22.2 years, 78.7% males and 21.3% females. Arrival time at hospital was 2.93 +/- 1.7 hours. 82.2% were in class I-II by NYHA. 59.2% had anterior wall location and 32.4% posterior-inferior wall 80% had reperfusion criteria. Only 7.1% required transfusion and 0.4% presented CNS bleeding. The survival rate was 95.2%. The mortality had no relation with bleeding. CONCLUSION: Fast infusion is an effective and safe method. Transfusion requirements are no greater, and CNS bleeding was noted in 0.4% of the cases.

Adult↗