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Biomedical subjects

J Caban

Publications and source records attributed to J Caban.

At least 19 recordsLinked to original sources
PubMed1998

[Remarks on injuries which were the source of tetanus and were based on observations from the Clinic of Infectious Diseases in Cracow].

From 1992 to 1996, 95 patients with tetanus were treated in the Chair and Department of Infectious Diseases in Cracow. Most of them came from rural area, and at old age (median 68 years). Small, trivial skin injuries were the most often identified portal of entry. Only few patients applied to doctor after injury for prophylaxis against tetanus. The authors emphasise that small skin injuries, which may be portal of entry for tetanus, should not be left abandoned.

Aged↗
PubMed1996

[Risk and circumstances in which people are bitten by dogs in Cracow-- observations from the Consulting Clinic of Infectious Diseases].

Inquiries about incidence of bites people by dogs have been made in the Consulting Ward for prophylactics of rabies of Chair and Department of Infectious Diseases in Cracow. There are frequent cases of people bitten by dogs, which usually occur in the streets. Victims are usually young. In the most cases there are not connection between victim's behavior and incidence. Dogs however bite without an understandable reasons frequently when they are controlled by their owners. The owners of the dogs often are not aware of their responsibility to prevent their dogs from biting passers-by.

Adolescent↗
PubMed1996

Natural human interferon alpha given orally has different effects on patients with distinct forms of chronic viral hepatitis B.

During therapy of chronic viral hepatitis B (CVHB), some patients treated with natural human interferon alpha (nHuIFN-alpha) lozenges failed to respond. These observations triggered studies aimed to determine whether there are markers predicting patients' response to therapy with nHuIFN-alpha lozenges. In these studies, 32 patients with CVHB were involved: 20 males and 12 females, 16-61 years of age with proven persistent hepatitis B viremia (HBV). Patients were evaluated for clinical, biochemical liver function, and virological markers of disease. During 300 days of treatment of the patients received 75-150 IU nHuIFN-alpha daily in form of lozenges. The responders to oral interferon therapy were those who had initially alanine amino transferase (ALAT) level higher than 100 IU (85.7% cure rate) and weak responses were observed among patients who had an initial ALAT level below 100 IU (9.0% response rate). Therefore, ALAT test in patients with CVHB may serve as a predicting indicator of the outcome of IFN lozenges therapy.

Administration, Oral↗
PubMed1996

[Evaluation of prognosis in purulent meningitis-myelitis based on the Glasgow Coma Scale].

We presented data from the investigation of the usefulness of the Glasgow Coma Scale in predicting the outcome of bacterial meningitis. Patients who aggregated high Glasgow Coma Scale scores had a good prognosis, whereas those patients with low scores had a very poor prognosis, inspite of this limitation the Glasgow Coma Scale seems to be a valuable supplement to the physical examination of patients with bacterial meningitis and may help in predicting the outcome of the disease.

Adult↗
PubMed1994

[Patients with tetanus from South-eastern Poland in material from the Clinic of Infectious diseases in Krakow in the years 1963-1992].

The incidence of tetanus is more frequent in South-Eastern Poland than other areas of the country. The patients are treated in Clinic of Infectious Diseases in Cracow. Our observations concern 869 patients of the last 30 years. In the years 1963-1972 young patients prevailed and the mortality rate was 28% in the years 1983-1992. 15% of the patients were below 50 years of the age and 44% were above the age of 70. The mortality rate in the latter period (the third decade) increased to 42%. The increase in the age of the patients is explained by the introduction of immunization against tetanus and the mortality rate increase by the greater frequency of respiratory failure and other complications of the disease and treatment in elderly patients.

Adolescent↗
PubMed1994

[Four cases of bacterial meningitis after epidural anesthesia].

Four patients with bacterial meningitis, previously anaesthetized epidurally, have been described. In one case the course of the disease was very serious and resulted in irreversible neurological lesion. Although epidural anaesthesia is considered to be a harmless procedure it can cause some purulent complications.

Adult↗
PubMed1993

Treatment of chronic viral hepatitis type B with oral mucosal administration of natural human interferon alpha lozenges.

Results of the administration of natural human interferon alpha (nIFN-alpha) into the oral cavity of 28 patients with chronic aggressive viral hepatitis type B are shown. Diagnosis of chronic aggressive viral hepatitis type B was based on clinical symptoms of disease, histopathological changes as evidenced by liver biopsy and persistence of HBV markers in patient sera. The daily dose of nIFN-alpha ranged from 75-200 IU/day. The twenty eight patients have been treated for a variable amount of time: thirteen over 300 days, two over 180 days, two over 120 days and eleven for less than 120 days. Only those patients who have been treated for over 300 days are considered to have completed the therapeutical program and remain under observation only. Oral IFN-alpha therapy is safe and efficacious in patients with chronic aggressive viral type B hepatitis. Among these 28 patients, 23 were initially positive for both hepatitis Bs antigen (HBsAg) and hepatitis Be antigen (HBeAg). Eight of these 23 patients have lost HBeAg and developed anti-HBe antibody. In addition one patient from this group seroconverted 356 days after initiation of treatment with IFN-alpha. Three patients lost HBs and HBe antigens and developed antibodies to both HBs and HBe antigens. Two patients who had eliminated HBe antigen before IFN-alpha therapy eliminated HBeAg following treatment and developed antibodies against HBs antigen. Three additional patients initially HBsAg+.HBcAg-, and HBeAg- developed antibody to HBe antigen during IFN-alpha therapy. At the time of this report 12 of the 23 initially viremic patients have seroconverted (52%).(ABSTRACT TRUNCATED AT 250 WORDS)

Administration, Oral↗
PubMed1990

[Detection of HIV antibodies among prisoners from penitentiary units within the district penal institutions in Cracow].

The reports on the high percentage of HIV infected persons in West European prisons brought about similar investigations in Kraków. 2794 prisoners and a control group of 241 people were examined. The authors used a questionnaire and detected HIV antibodies. The number of seropositive prisoners was not essential. The value of structure factor was 0.15% for prisoners, and in the control group it was 0%. The value of the test u = 0.64, statistical differences were not significant - p greater than 0.05.

Acquired Immunodeficiency Syndrome↗
PubMed1990

[Tetanus patients treated at the Infectious Disease Clinic, Medical Academy, in Cracow 1980-1989].

In this period 257 tetanus patients was treated. The majority of them being old age farmers. 44% patients treated in our clinic were over 71 years old. They were not actively immunized against tetanus. The principal percentage of mortality was high (42%), but it was clearly correlated with old age of patients. The co-existed diseases and complications had influence to unprofitable results of treatment. Comparing 3 last tenth anniversary--general number of tetanus patients demonstrated insignificant decrease and an important increase among cases of patients more than 71 years old. Tetanus is still seriously menace to unvaccinated people in Poland.

Adult↗
PubMed1990

[Patients with severe tetanus treated in the department of infectious diseases in 1986-1988].

The results of treatment of patients with tetanus having severe clinical course observed in Department of Infectious Diseases in Cracow 1986-1988 have been presented. The documentation of 30 patients with tetanus undergoing intensive therapy has been analysed. The mean age of patients was 64 years. In 26 patients the controlled respiration has been used. These patients have been treated moreover by muscular relaxants such as Pavulon or rarely the tubocurarine derivatives. Among patients treated 16 deaths were noted and 14 cases were recovered.

Adult↗