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Biomedical subjects

J Caballero

Publications and source records attributed to J Caballero.

43 records · Page 3Linked to original sources
PubMedDate not supplied

[Rett's syndrome in the Spanish population].

INTRODUCTION AND OBJECTIVE: Rett syndrome was described in 1966 and became known through the English medical literature in 1983. There are typical and atypical forms. The objective of this study was to record the cases diagnosed in Spain and discover their clinical characteristics in order to describe its phenotype and geographical distribution. PATIENTS AND METHODS: We know of 207 cases and have obtained the records of 168 of these patients. A protocol and data collection programme has been developed giving the criteria for inclusion, and data which support or exclude this. Data collection was by post and the data for identification were the date of birth and the initials of the name and two surnames. With these variables, double-registering of patients was almost impossible. A statistical study with descriptive analysis and a study of continuous and alternating variables was immediately done. RESULTS AND CONCLUSION: The results gave the main characteristics, the differences between typical and atypical cases and a comparative study of variables. It has given clinical data which may be useful for prognosis of the condition in the future.

Adolescent↗
PubMedDate not supplied

Attitudes regarding tuberculosis in immigrants from the Philippines to the United States.

BACKGROUND AND OBJECTIVES: More than two thirds of the cases of tuberculosis (TB) in the United States occur in non-white minorities and immigrants. The Philippines is the Asian country of origin with the greatest numbers of TB cases among the foreign-born. This paper explores Filipino knowledge, attitudes, and practices concerning TB. METHODS: Four focus groups of Filipino immigrants were convened to discuss the participants' explanatory models regarding TB. The results of these groups were reviewed by a panel of Filipino health workers. RESULTS: The focus group participants expressed a belief in the extreme contagiousness of TB. This leads to social stigma and isolation. The desire to avoid such consequences lead some to deny their illness, not seek attention, or attempt to hide their illness. While all agree that biomedical treatment is necessary, many believe in the effectiveness of traditional and popular treatments. CONCLUSIONS: If explanatory models of illness are elicited from individual patients, an understanding of the shared beliefs regarding tuberculosis in Filipinos may contribute to treatment of these patients.

Adult↗
PubMedDate not supplied

[Venlafaxine extended release for the treatment of chronic pain. A series of 50 cases].

INTRODUCTION: The objective of this study is to investigate analgesic effectiveness and safety of venlafaxine extended release in chronic pain of any etiology. METHODS: Six month, observational, open study, carried out in two pain units. Initially, a daily dose of 75 mg of venlafaxine extended release was administered, increasing it to 150 mg, following clinical criteria. Treatment response was measured using the Visual Analogue Scale (VAS), rest and mobilization, Hospital Anxiety and Depression Scale (HAD) and Eastern Cooperative Oncology Group (ECOG) and an adverse event sheet to record adverse events occurring during the study. RESULTS: The study was carried out in a 50 patient sample with a mean age of 57.1 +/- 1.8 years, with chronic pain. A total of 85-90 % of the patients was maintained with a daily dose of 75 mg of venlafaxine extended release. This produced a gradual reduction of the VAS scores at rest (significant reduction of 5.2 +/- 1.1 to 2.7 +/- 1.5 points; (p<0.0005) and mobilization (significant reduction of 5.5 +/- 0.8 to 3.1 +- 1.6 points; p<0.0005). Pain relief increased progressively. Regarding physical activity measured by the ECOG scale, there was a reduction of the percentage of patients and increase of outpatients. Tolerability to venlafaxine was "excellent", "very good" or "good" for 72% of the patients. CONCLUSIONS: Extended release venlafaxine can be an effective and well-tolerated treatment in patients with chronic pain of any etiology, although it must be investigated in depth.

Adult↗
PubMedDate not supplied

[Multiple paragangliomas. The problem of its localization. Report of the first case studied with 131I meta-iodobenzylguanidine in our milieu and review of the literature].

We report the case of a young woman, with an 8 year history of paroxysmal episodes of dyspnea, palpitations, blurred vision, tremors, precordial oppression and hypertension; the diagnosis of a chromaffin tumor was established, with an increase in serum and urine catecholamines level. She had three surgical interventions and also the following studies: abdominal and pelvic ultrasound, computed tomography, cavography; selective arteriography, and infusion of the meta iodobenzyl-guanidine 131, which localizes tissues hypersecretors rich in catecholamines.

3-Iodobenzylguanidine↗