Analogue device for measurement of area under the maximum expiratory flow-volume curve.
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Biomedical subjects
Publications and source records attributed to J C Vermaak.
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An on-line computerised lung function screening test is described which prints out 22 lung function parameters and a functional diagnosis. The complete test with print-out data takes less than 8 min per patient which implies that more than 60 out-patients can be 'screened' per day. Furthermore, for patients about to undergo major surgery a lung function operative risk grading is also available. The developed computer system is comparatively inexpensive, simple to operate and can be immediately on-lined to most apparatus without special interfacing. The total screening system can be operated by a single technologist and the required respiratory manoeuvres can be performed by almost all patients irrespective of the degree of lung function impairment. Although comprehensive in itself the screening test has been invaluable in deciding upon which patients require more intensive and time-consuming lung function investigations.
A new lung function index, the area under the maximum expiratory flow-volume curve (AFVx) is described. A predicted AFVx based on age, sex and height is determined, and the measured to predicted AFVx ratio is assessed by comparison with other established lung function parameters. This ratio appears to be a very sensitive indicator of the degree of lung function impariment.
Records of a possible relationship between intraluminal pressure profiles and movements of the mucosal layer are not obtainable. A prospective study was initiated to investigate this aspect in the pyloric region of the stomach and in the duodenum. The results indicate that simultaneously with certain contraction waves of the walls, all mucosal folds within the confines of the contraction change in direction to become longitudinal, thus forming longitudinal intraluminal mucosal troughs. (It is presumed that these will enhance linear flow of semiliquid intestinal contents.) The phenomenon occurs regularly and is an inherent component of various contraction waves, including peristalsis. The definition of peristalsis should probably be expanded to include reference to this mucosal component. These normal findings may serve as a base line for the investigation of mucosal motility patterns in pathological situations, e.g. peptic ulcer.
A method for the measurement of recognised lung function parameters is described. Bedsides being useful for the detection of early pathology, the information obtained by this method is generally sufficient for an early diagnosis. A large number of patients can be examined per day and the test is also informative in high-risk pre-operative patients. Furthermore, the method is suitable for epidemiological studies and has already been used by the Medical Research Council to determine the incidence of chronic obstructive lung disease in the Bellville area.